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Protein Overview: ade8

General Information:
Name(s) found: ade8 / SPBC14F5.09c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • adenylosuccinate lyase Ade8 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 482 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: purine nucleotide biosynthetic process [ISSLink to PubMed article]
    'de novo' IMP biosynthetic process [ISSLink to PubMed article]
    Molecular Function: N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity [ISSLink to PubMed article]
    (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDYGSYSTP LTARYASAEM SHLFSREMRI NTWRQLWLNL AIAEKQLGLT QITDEAIEQL  60
   61 KAHVKITAPE FEIAAKEEKR QRHDVMAHIY TYGLAAPAAS GIIHLGATSC FVTDNADLIF 120
  121 LRSAMDLLIP KLVNVINRLS QWSLRYKDIP TLGFTHYQPA QLTTVGKRAT LWIQELLWDL 180
  181 RNFVRARNDI GFRGVKGTTG TQASFLALFE GDHAKVEELD KLVAKLSGFD NVYPVTGQTY 240
  241 DRKIDIDVLQ PLASFGATAH KIATDIRLLA NLKEVEEPFE AGQIGSSAMA YKRNPMRCER 300
  301 ICSQARYIMN LIPNALNTAS VQWFERTLDD SSNRRSLLPE AFLFTDSVLK ILLNVISGMV 360
  361 IYPKVIQKHI RAELPFMATE NIIMAMTKHG ASRHECHEQI RVLSHQAGRV VKEEGGDNDL 420
  421 IERIKNTPYF APIYDELDSL LDASTFVGRA PEQTESFVNK DVSQALAPFK SMITEEKVDL 480
  481 AV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..482] PSI-BLAST 115.0 No description for 2j91A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.52

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle