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Protein Overview: ade3

General Information:
Name(s) found: ade3 / SPAC6F12.10c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • phosphoribosylformylglycinamidine synthase Ade3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1323 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed articleLink to PubMed article]
    Golgi apparatus [IDALink to PubMed article]
    Biological Process: purine nucleotide biosynthetic process [ISSLink to PubMed article]
    'de novo' IMP biosynthetic process [ISSLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    phosphoribosylformylglycinamidine synthase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVYYGGSAL SVQSKKKILE LTVSGVSDLN AVYFYLIYTK SNSSLNCESL RPILSDLQES  60
   61 EFKPDGTTMV YVFPRPGTIS PWSSKATNIA NVCGYKDVIR IERGIAYSVV FKDDISEEML 120
  121 KSALNHLYDR MTEALRFKLP EEDEVFDKHE PAPLVRIELN CGQGGDKQAA TERLNHANKK 180
  181 FGLALAPDEI DYLVECYTSE PSLKSREPTD VELFMFGQVN SEHCRHKIFN ADWTIDGEKK 240
  241 DYSLFKMIRN THLKNPQYTI SAYSDNAAVF EGNSGTLFAP VNGIWSMKDE PVEFLGKVET 300
  301 HNHPTAVSPF PGAATGSGGE IRDEGAVGQG SLSKAGLAGY SVSDLNIPGY KQPWELDVGK 360
  361 PYHIATSLDI MLEAPIGSSA FNNEFGRPCI NGYFRTFCME VPRGDGTLEI RGYHKPIMAA 420
  421 GGIGRIRKQH AFKKSIAPGS PIIVLGGPAL LVGLGGGAAS SMNAGEGSEE LDFASVQRGN 480
  481 PEMQRRAQMV IDACTTMDEN IIQSIHDVGA GGVSNALPEL VHDAGLGARF ELRDIPCIEP 540
  541 SMSPMQIWCC ESQERYVLSV KSEDLDTFKS ICERERCPYG VVGYSTVEQR LILTDRLYNT 600
  601 TPIDLPMEVL FGKPPKMSRV AETQTIPLSK FDSSLKSYLA PSSDPILDAV ERVLRMPAVA 660
  661 SKSFLITIGD RSVTGLIARD QMVGPWQVPV ADVGVTVTSY GKGINTGEAL AMGEKPISAL 720
  721 VSAAASARMA VAECIMNLVA ASIPALDRIR LSANWMAAPS HPGEGAKLYE AVQAIGLELC 780
  781 PSLGISIPVG KDSMSMSMKW NEDGREKSVT APLSLIITGF SPVDDLYSIW TPQLRKVEDI 840
  841 GSTSLIFIDL ANGKQRLGGS ILAQSYKQLG DEVPDLDNLD TFKNFINVIT QLHKTNYIQA 900
  901 YHDKSDGGLF VTLSEMAFAG HVGIECELDS LSSDNIAALF NEELGAVIQV CDRDIAKVLE 960
  961 LFAANGLSTC VHRIGKVLSG QAQTISFSRS GKIIFKSTRS KLHGIWHETS YKMQEIRDNP1020
 1021 ECARQEMENI ADNNDPGLGY HLTFDPNVSV TADLALTSRP KVAILREQGV NGYLEMAYAF1080
 1081 YASGFTAVDV HMTDILSGRV HLDDFVGIAA CGGFSYGDVL GSGNGWATSI LLHEDARNEF1140
 1141 YRFFNERKDT FGLGICNGCQ LFSRLKSLIP GAKSWPMFTF NESAQYEGRA VMLKIDETSG1200
 1201 SKSIFTESMA GSSLPVVVAH GEGRAVFDSE SDYEQFKKEG LDLIYYVNNY NERTSRYPFN1260
 1261 PNGSRDAIAG VRSPCGRFLA MMPHPERVVL KVANSYYPHS KASEWGVHGP WIRLFQSARK1320
 1321 WVG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1323] PSI-BLAST 1000.0 Structure of Formylglycinamide synthetase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoribosylformylglycinamidine cyclo-ligase activity
    		•  3.04322905277855 bayes_pls_golite062009
  • cyclo-ligase activity
    		•  2.40623349460413 bayes_pls_golite062009
  • carbamoyl-phosphate synthase activity
    		•  1.74828881793189 bayes_pls_golite062009
  • carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
    		•  1.74029540439985 bayes_pls_golite062009
  • binding
    		•  1.31749052462602 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  0.78656048097577 bayes_pls_golite062009
  • catalytic activity
    		•  0.317253455922165 bayes_pls_golite062009
  • protein binding
    		•  0.288540446972424 bayes_pls_golite062009
  • phosphoribosylformylglycinamidine synthase activity
    		•  0.268823253442304 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.12569720972861 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.74

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle