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Protein Overview: spp2

General Information:
Name(s) found: spp2 / SPBC17D11.06 [Sanger Pombe]
Description(s) found:
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  • pir||T39717 probable dna primase large subunit - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|3650405|emb|CAA21077.1| DNA primase large subunit Spp2 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|34395750|sp|O74761.1|PRI2_SCHPO RecName: Full=DNA primase large subunit [NCBI NR]
  • gi|19113172|ref|NP_596380.1| DNA primase large subunit Spp2 [Schizosaccharomyces pombe] [NCBI NR]
  • DNA primase large subunit Spp2 [Sanger Pombe]
  • DNA primase large subunit OS=Schizosaccharomyces pombe GN=pri2 PE=1 SV=1 [Swiss-Prot]
  • DNA PRIMASE LARGE SUBUNIT: O74761;Q9US83; [pompepVF.fasta]
  • DNA primase large subunit (EC 2.7.7.-) [pompep4896]
  • |pri2||DNA primase large subunit [pompepnew.fasta]
  • |spp2|pri2|DNA primase (large subunit) (PMID 11027257)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative dna primase large subunit [Schizosaccharomyces pombe]gi|3650405|emb|CAA21077.1| SPBC17D11.06 [Schizosaccharomyces pombe]gi|34395750|sp|O74761|PRI2_SCHPO DNA primase large subunitgi|7492530|pir||T39717 probable dna primase large subunit - fissi [nrdb_11152004_Chlamydomonas]
  • |spp2|pri2|DNA primase large subunit |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O74761) DNA primase large subunit (EC 2.7.7.-) [pompep4896_normal_reversed]
  • |spp2|pri2|DNA primase large subunit Spp2|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • DNA primase large subunit [nr-271106-contam.fasta]
  • SPBC17D11.06 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC17D11.06 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • DNA primase large subunit OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pri2 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 459 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    alpha DNA polymerase:primase complex [TASLink to PubMed article]
    nuclear chromatin [ICLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    nuclear replication fork [ICLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: telomere maintenance [IMPLink to PubMed article]
    cell cycle [RCALink to PubMed article]
    DNA replication, synthesis of RNA primer [TASLink to PubMed article]
    Molecular Function: DNA primase activity [IEA]
    DNA binding [IEA]
    iron ion binding [IEA]
    4 iron, 4 sulfur cluster binding [IEA]
    iron-sulfur cluster binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRTTKSRVV EKNQNFSSAS FESLSYPTRL NFYKKPPVSE ISIEEFETWA IDRLVVLGEI  60
   61 ESAMLRNKTK NELNGIIKKI LDKRLPMSSN MARTVKGNSL DEERRKDHYS HFILRLAFSR 120
  121 SDELRIRFLR AESTLFRFRF VNEETRERQA FIDSLDFQWE SVSQEEKDVF YEKLQASSQR 180
  181 NIENESFFKV PFFKVPDLVE RRAVFVHKGY AYVPFSEQVS LVVEEFEENL KKALESTAKS 240
  241 LPRLDEDDRL LPILNHLSKG FVAPESSIVA PKSGAITAGQ VDSFVSHFPL CAKHLHEVLK 300
  301 RDKHLRHFGR LQYGLFLKDI GLSVDEALVF WRKSFTNVTE DKFNKEYRYN IRHTYGLEGN 360
  361 RKNYKGYNCQ QILTGPQLGP GDAHGCPYRT YSVNNLVSAL ASMGIAPDSA GCREVVEAVK 420
  421 ARHYHIACTR VFELTHPNVG SLEESIHHPL QYFQLSLES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..95] MSA 1.060979 View MSA. No confident structure predictions are available.
    2 View Details [96..240] PSI-BLAST 4.0 Heterodimeric structure of the core primase.
    3 View Details [241..459] MSA 2.070996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle