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Protein Overview: pof3

General Information:
Name(s) found: pof3 / SPCC338.16 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • F-box protein Pof3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 577 amino acids

    Gene Ontology:
    Cellular Component: ubiquitin ligase complex [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    chromosome [IEA]
    Biological Process: telomere maintenance [IMPLink to PubMed article]
    ubiquitin-dependent protein catabolic process [ISS]
    Molecular Function: protein binding [IPILink to PubMed article]
    protein binding, bridging [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNYQVKAIK EKTQQYLSKR KFEDALTFIT KTIEQEPNPT IDLFELRAQV YEKSGQYSQA  60
   61 ELDAKRMIHL NARNARGYLR LGKLLQLDGF DKKADQLYTQ GLRMVHKMDP LRPVLKKVSQ 120
  121 RLNERILRTR PVLDLFRILP REVLLCILQQ LNFKSIVQCM QVCKHWRDCI KKEPSLFCCL 180
  181 DFSCASPRSV NSRDRNVMAV ARYSVYSKDN IQEVIGLEKL GILTPTKALL RSVKSLKVYK 240
  241 TISPLHTQST DKLYTIWTPF SELHYFYCAT PITFSIASKI LSCCKKLKQV ELVDLIPDLI 300
  301 FDSMDWDKLF NAESVPLALK SLTFIRNQKF PFHHKEQQFL KDLLSASPYL EYLEASYQSD 360
  361 LVAAIKKYKI NLRSLIIIDE GVSNTVKDLA FLPQSLTTLI VKPCNPASTI LCPYLFPTNV 420
  421 RMESLINLEL FLYLRLSQND IDNVVKFLTS CYKLKKLVLH DSLALAPHFF EIFASLPELE 480
  481 HLEIPDNVAL QNKHAIHITD CCPNLKYVNF SNSISLDGSG FIAVLRGLKE LKRIDIINCD 540
  541 SVSRDAIDWA RSKGMQVTVA SSLPNSQPLG TKKIRLI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..308] PSI-BLAST 50.0 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
    2 View Details [309..380] PSI-BLAST 3.522879 No description for 2ifuA was found.
    3 View Details [381..577] FFAS03 3.57 Skp2; Cyclin A/CDK2-associated p19, Skp2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  4.81092926633672 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  4.73323750175899 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.038463864925 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  3.25461549315207 bayes_pls_golite062009
  • binding
    		•  2.09193012129784 bayes_pls_golite062009
  • ligase activity
    		•  1.72049482453565 bayes_pls_golite062009
  • protein binding
    		•  1.52807685989528 bayes_pls_golite062009
  • hydrolase activity
    		•  0.619711232527193 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.0195797944362903 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle