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View Structure Prediction Details

Protein: pof3
Organism: Schizosaccharomyces pombe
Length: 577 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pof3.

Description E-value Query
Range
Subject
Range
gi|48892684, gi|... - gi|71675161|ref|ZP_00672907.1| Peptidase S1, chymotrypsin:TPR repeat [Trichodesmium erythraeum IMS10...
246.0 [0..1] [330..319]
gi|56967372, gi|... - gi|62821820|ref|NP_001017359.1| O-linked N-acetylglucosamine transferase isoform 1 [Danio rerio], gi...
236.0 [0..2] [393..85]
gi|76659271 - gi|76659271|ref|XP_884992.1| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 7 [...
235.0 [0..2] [393..85]
gi|74007684 - gi|74007684|ref|XP_858918.1| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 11 ...
233.0 [0..2] [393..85]
gi|31873825 - gi|31873825|emb|CAD97853.1| hypothetical protein [Homo sapiens]
232.0 [0..2] [393..85]
gi|13775066 - gi|13775066|gb|AAK39123.1|AF363030_1 UDP-N-acetylglucosaminyltransferase [Mus musculus]
232.0 [0..2] [393..85]

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Predicted Domain #1
Region A:
Residues: [1-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNYQVKAIK EKTQQYLSKR KFEDALTFIT KTIEQEPNPT IDLFELRAQV YEKSGQYSQA  60
   61 ELDAKRMIHL NARNARGYLR LGKLLQLDGF DKKADQLYTQ GLRMVHKMDP LRPVLKKVSQ 120
  121 RLNERILRTR PVLDLFRILP REVLLCILQQ LNFKSIVQCM QVCKHWRDCI KKEPSLFCCL 180
  181 DFSCASPRSV NSRDRNVMAV ARYSVYSKDN IQEVIGLEKL GILTPTKALL RSVKSLKVYK 240
  241 TISPLHTQST DKLYTIWTPF SELHYFYCAT PITFSIASKI LSCCKKLKQV ELVDLIPDLI 300
  301 FDSMDWDK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.0
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 4.81092926633672 bayes_pls_golite062009
small conjugating protein ligase activity 4.73323750175899 bayes_pls_golite062009
acid-amino acid ligase activity 4.038463864925 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 3.25461549315207 bayes_pls_golite062009
binding 2.09193012129784 bayes_pls_golite062009
ligase activity 1.72049482453565 bayes_pls_golite062009
protein binding 1.52807685989528 bayes_pls_golite062009
hydrolase activity 0.619711232527193 bayes_pls_golite062009
nucleic acid binding 0.0195797944362903 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [309-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LFNAESVPLA LKSLTFIRNQ KFPFHHKEQQ FLKDLLSASP YLEYLEASYQ SDLVAAIKKY  60
   61 KINLRSLIII DE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 2ifuA
Description: No description for 2ifuA was found.

Predicted Domain #3
Region A:
Residues: [381-577]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVSNTVKDLA FLPQSLTTLI VKPCNPASTI LCPYLFPTNV RMESLINLEL FLYLRLSQND  60
   61 IDNVVKFLTS CYKLKKLVLH DSLALAPHFF EIFASLPELE HLEIPDNVAL QNKHAIHITD 120
  121 CCPNLKYVNF SNSISLDGSG FIAVLRGLKE LKRIDIINCD SVSRDAIDWA RSKGMQVTVA 180
  181 SSLPNSQPLG TKKIRLI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.57
Match: 1fs2A
Description: Skp2; Cyclin A/CDK2-associated p19, Skp2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle