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Protein Overview: shk1

General Information:
Name(s) found: shk1 / SPBC1604.14c [Sanger Pombe]
Description(s) found:
Found 22 descriptions.
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  • PAK-related kinase Shk1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 658 amino acids

    Gene Ontology:
    Cellular Component: spindle microtubule [IDALink to PubMed article]
    cell division site [IDALink to PubMed articleLink to PubMed article]
    cell tip [IDALink to PubMed articleLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: regulation of establishment or maintenance of cell polarity [IGILink to PubMed articleLink to PubMed article]
    regulation of microtubule cytoskeleton organization [IGILink to PubMed article]
    small GTPase mediated signal transduction [IGILink to PubMed article]
    regulation of cytokinesis [IMPLink to PubMed article]
    activation of bipolar cell growth [IMPLink to PubMed article]
    establishment or maintenance of actin cytoskeleton polarity [TASLink to PubMed article]
    protein amino acid phosphorylation [IEA]
    cellular protein localization [IGILink to PubMed article]
    Molecular Function: ATP binding [IEA]
    protein binding [IPILink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    protein serine/threonine kinase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERGTLQPRK KAPNGYGITP IVAHKTGEPV RYEVEDDLRK LKPSRTAPKP PAINTNLAED  60
   61 TFSGFPLSQS RTTVSRVSLG SRQHSSSSIR KLQTNVSDVR SYDERNQKKS AFENFVSSMS 120
  121 SFLTGGGSSP TSSYGSGSAS PRKSTVISSP FDPKHVTHVG FNYDTGEFTG MPTEWQALLK 180
  181 VSGITKSEQV QHPQAVLDAM AFYSQSKKYL EEGAKPPFPR ESTEKPLLSV SALSSSSHLQ 240
  241 PTSATSSSSR LYPSRPAPTP PASSSSSPLL SSQTVKTTTS NASRQPSPLV SSKSTDNIIR 300
  301 SHSPVLLTPQ TLSTSETKHI RPNNSTPYQR RAETSTKPKA VATPQKVEAP SAPRLQKRAP 360
  361 RQQSNDSAVL AKLQSICNPK NPTLLYRNFV KIGQGASGDV YSARQVGTNL SVAIKKMNIN 420
  421 QQPKKEFIVN EILVMKSHHH KNIVNFIDTF FYKSELWMVM EYMRGGSLTE VVTNNTLSEG 480
  481 QIAAICKETL EGLQHLHENG IVHRDIKSDN ILLSLQGDIK LTDFGFCAQI DSNMTKRTTM 540
  541 VGTPYWMAPE VVTRKEYGFK VDVWSLGIMA IEMVEGEPPY LNENPLRALY LIATIGTPKI 600
  601 SRPELLSSVF HDFLSKSLTV NPKQRPSSGE LLRHPFLKQA VPVSSLIPLI KSIHHSGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..64] deduced N/A No confident structure predictions are available.
    2 View Details [65..240] FFAS03 4.05 pak1 autoregulatory domain
    3 View Details [241..379] deduced N/A No confident structure predictions are available.
    4 View Details [380..658] PSI-BLAST 81.522879 pak1


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle