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Protein Overview: pac1

General Information:
Name(s) found: pac1 / SPBC119.11c [Sanger Pombe]
Description(s) found:
Found 26 descriptions.
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  • double-strand-specific ribonuclease Pac1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 363 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nucleolus [ISSLink to PubMed article]
    Biological Process: snRNA processing [IMPLink to PubMed article]
    rRNA processing [IMPLink to PubMed article]
    regulation of conjugation with cellular fusion [IMPLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    ribonuclease III activity [TASLink to PubMed article]
    RNA binding [ISSLink to PubMed article]
    double-stranded RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRFKRHHEG DSDSSSSASD SLSRGRRSLG HKRSSHIKNR QYYILEKKIR KLMFAMKALL  60
   61 EETKHSTKDD VNLVIPGSTW SHIEGVYEML KSRHDRQNEP VIEEPSSHPK NQKNQENNEP 120
  121 TSEEFEEGEY PPPLPPLRSE KLKEQVFMHI SRAYEIYPNQ SNPNELLDIH NERLEFLGDS 180
  181 FFNLFTTRII FSKFPQMDEG SLSKLRAKFV GNESADKFAR LYGFDKTLVL SYSAEKDQLR 240
  241 KSQKVIADTF EAYLGALILD GQEETAFQWV SRLLQPKIAN ITVQRPIDKL AKSKLFHKYS 300
  301 TLGHIEYRWV DGAGGSAEGY VIACIFNGKE VARAWGANQK DAGSRAAMQA LEVLAKDYSK 360
  361 FAR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..104] MSA 3.104989 View MSA. No confident structure predictions are available.
    2 View Details [105..363] PSI-BLAST 52.69897 RNase III endonuclease catalytic domain; RNase III, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • RNA binding
    		•  3.49736268261512 bayes_pls_golite062009
  • binding
    		•  3.09705138687537 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.95361490759242 bayes_pls_golite062009
  • endoribonuclease activity
    		•  1.62086478301433 bayes_pls_golite062009
  • DNA binding
    		•  1.51133867432475 bayes_pls_golite062009
  • double-stranded RNA binding
    		•  1.46317494664076 bayes_pls_golite062009
  • protein binding
    		•  1.33336414936007 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.33042413200827 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.25950932467779 bayes_pls_golite062009
  • structural molecule activity
    		•  1.17628321323282 bayes_pls_golite062009
  • transcription factor activity
    		•  0.42419387757895 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle