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Protein Overview: sod22

General Information:
Name(s) found: sod22 / SPAC3A11.09 [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • plasma membrane alkali metal cation/H+ antiporter Sod22 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 759 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    plasma membrane [IGILink to PubMed article]
    Biological Process: cellular potassium ion homeostasis [IGILink to PubMed article]
    proton transport [ICLink to PubMed article]
    Molecular Function: potassium ion transmembrane transporter activity [IGILink to PubMed article]
    sodium:hydrogen antiporter activity [IGILink to PubMed article]
    sodium ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAWSQVEISK PHLAYAIIGG FTSLFMLCSL IIKEKLFLGE ATMATATGLI FGPYVAKLFV  60
   61 PTSWGNTDYI TEELARVLLV VEVFAAGAEL PRAYMLRHWR SMFVMLLPVM IFGWLVSTGF 120
  121 MYALIPRLSF LESLAIAACI TATDPVLASS IVGKGKFARR VPGHLRNMLL AESGCNDGMA 180
  181 IPFLYLAIYL IIEKPARHAG RDWVCIIILY ECTFGCVLGA IIGVIARKMI KFSERRGLMD 240
  241 RESFLVFYFV LALFCGGIGT IIGVDDLLVS FCAGAAFSWD SWFSKKTEES HVSNVIDLLL 300
  301 NLSFFVYVGA IMPWPQFHMP HMDLSVWRLV VLAICILIAR RIPAVLLFKS FVPDIINWRE 360
  361 ALFAGHFGPI GVGALYTCLV ARAELEVHST VPEPNDAIEN PEIPNWYCIQ VMWPVVCFLV 420
  421 LSSIIVHGSS IAFFMLGKRI NTLALSFTRT RDSHFAFNLP RVRQGQSLPI KRVDALRSSA 480
  481 NSIASSIRRR HPVNIQEDED ADISTVSLPE AAHLREERAE SPRGGHYDAE EFPSEDYESR 540
  541 QPRRSNEEDR EEEMNPGDET YLIGEDLVVE DSQGNIISHT SSRDANGPSI DEKLAQGDPK 600
  601 AKSFGRKFRS FLRRSYDTFQ RNLHEPDDER QREPTLGHIE SSIENHRPRY SRQNSESHLR 660
  661 ENSVERRRRE QVLTNIGDSE SEDDNIPRPG IVPFYNENNE SSSDTRNGLL SDNVSESRSR 720
  721 RPSRAPSAAV SSEGSPVEED NEAQHRPNIR FLELTRAWE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..282] PSI-BLAST 58.0 Mitochondrial cytochrome c oxidase, subunit I
    2 View Details [283..488] FFAS03 1.06 Formate dehydrogenase N, cytochrome (gamma) subunit
    3 View Details [489..759] FFAS03 1.65 30S subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • hydrogen ion transmembrane transporter activity
    		•  7.50940473108878 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  5.81094633113969 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  5.47229089392626 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.38267095422061 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.98308064247273 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  4.94646483547119 bayes_pls_golite062009
  • transporter activity
    		•  3.25025513931324 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.15068691999889 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.13647909964298 bayes_pls_golite062009
  • binding
    		•  0.979727257352345 bayes_pls_golite062009
  • protein binding
    		•  0.291685656235254 bayes_pls_golite062009
  • ubiquinol-cytochrome-c reductase activity
    		•  0.143276144501499 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
    		•  0.143276144501499 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle