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Protein Overview: mts4

General Information:
Name(s) found: mts4 / SPBP19A11.03c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • 19S proteasome regulatory subunit Mts4 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 891 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][TASLink to PubMed article]
    proteasome regulatory particle, base subcomplex [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: proteasomal ubiquitin-dependent protein catabolic process [IGILink to PubMed article]
    regulation of catalytic activity [IC]
    regulation of protein catabolic process [IEA]
    regulation of cell cycle [RCALink to PubMed article]
    mitotic cell cycle [IC]
    Molecular Function: protein binding [IPILink to PubMed article]
    endopeptidase activity [ISSLink to PubMed article]
    enzyme regulator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKDISSKS PSGNDALNDK KGTKTSETND RNSTNNTKER DELEDLSEED LQLKNDLELL  60
   61 VQAVQDATPE LVGSSLTQLK EIIRTSTSSM TAVPKPLKFL RPHYFTLVKI YDSWPQSPQK 120
  121 TQLADILSVL GMSYSNTSKH ESLKYRLQGV TTDPSLWGHE YVRHLASEIE EEFASRQEEE 180
  181 APTDDLMELA LTIVPFFLTH NAEADAIDLL QELGAIEKVV PFVELDNASR VCLYITSCVN 240
  241 LLPFPEDVAM LRTAHAIYRK FDQLTQALNV AIRLDDMSLI KEDCEAATDP LLKKQMSYML 300
  301 ARQQIPMDMG DEELNDALNN THLSDHFHYL GKELNLMDPK VPEDIFKTHL EVARTGLGAS 360
  361 GVYSAKQNLA NTFVNALVNA GYSNDRLILV DDEKTSWIYK NKESGLISAT ASIGLLQLWN 420
  421 VDMGLSLLDK YLYSSEENTK AGALLGIGVT NVAVRNEADP AMAILSEYLE TGSVKLRASA 480
  481 ILGLGLAYSG ANREDLLDML SPIVTDTDCP MQLSCLAALS LGLIFVGTCN GDVASTILQT 540
  541 LMEREESAQN DQWGRFMALG LALLFNGKQD LADATVETLK AIEGKIARQA EILVDICSYA 600
  601 GTGNVLHIQK LLHICSEPPS DDAKESETTI QTFAALGVAT IAMGEDIGAE MVLRHFDHMM 660
  661 HYGEPSIRKA IPLALGLLSA SNPQMRIFDT LSRYSHDNDL DVAYNAIFAM GLVGAGTSNA 720
  721 RLAQLLRQLA SYYHKESNAL FMVRIAQGLL YLGKGTMTLN PYHTERQILG QTAFAGLMTV 780
  781 VLAMLDANTF VLDTSHWLLY AITLAIRPRM LITLGEDGQY LPVSVRVGQA VDVVGQAGRP 840
  841 KVITGWVTHT TPVLLHHNER AELATEAYTP LTSLEGIVIL KKNTEDIEMT A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..200] PSI-BLAST 5.39794 Crystal Structure of Anthrax Lethal Factor complexed with (3-(N-hydroxycarboxamido)-2-isobutylpropanoyl-Trp-methylamide), a known small molecule inhibitor of matrix metalloproteases.
    2 View Details [201..716] PSI-BLAST 59.39794 No description for 2pkgA was found.
    3 View Details [717..785] PSI-BLAST 20.0 Mouse Importin alpha- phosphorylated SV40 CN peptide complex
    4 View Details [786..891] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.41

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle