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Protein Overview: cdc25

General Information:
Name(s) found: cdc25 / SPAC24H6.05 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • serine/threonine protein phosphatase Cdc25 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 596 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: DNA replication checkpoint [IMPLink to PubMed article]
    G2/M transition of mitotic cell cycle [NASLink to PubMed article]
    protein amino acid dephosphorylation [ICLink to PubMed article]
    regulation of cell size [NAS]
    positive regulation of cyclin-dependent protein kinase activity involved in G2/M [TASLink to PubMed article]
    regulation of G2/M transition of mitotic cell cycle [IMPLink to PubMed article]
    Molecular Function: phosphoprotein phosphatase activity [IDALink to PubMed article]
    protein binding [IPILink to PubMed articleLink to PubMed article]
    protein tyrosine phosphatase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSPLSSLSF TNTLSGKRNV LRPAARELKL MSDRNANQEL DFFFPKSKHI ASTLVDPFGK  60
   61 TCSTASPASS LAADMSMNMH IDESPALPTP RRTLFRSLSC TVETPLANKT IVSPLPESPS 120
  121 NDALTESYFF RQPASKYSIT QDSPRVSSTI AYSFKPKASI ALNTTKSEAT RSSLSSSSFD 180
  181 SYLRPNVSRS RSSGNAPPFL RSRSSSSYSI NKKKGTSGGQ ATRHLTYALS RTCSQSSNTT 240
  241 SLLESCLTDD TDDFELMSDH EDTFTMGKVA DLPESSVELV EDAASIQRPN SDFGACNDNS 300
  301 LDDLFQASPI KPIDMLPKIN KDIAFPSLKV RSPSPMAFAM QEDAEYDEQD TPVLRRTQSM 360
  361 FLNSTRLGLF KSQDLVCVTP KQSTKESERF ISSHVEDLSL PCFAVKEDSL KRITQETLLG 420
  421 LLDGKFKDIF DKCIIIDCRF EYEYLGGHIS TAVNLNTKQA IVDAFLSKPL THRVALVFHC 480
  481 EHSAHRAPHL ALHFRNTDRR MNSHRYPFLY YPEVYILHGG YKSFYENHKN RCDPINYVPM 540
  541 NDASHVMTCT KAMNNFKRNA TFMRTKSYTF GQSVLASPDV NDSPTAMHSL STLRRF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] deduced N/A No confident structure predictions are available.
    2 View Details [154..203] MSA 1.050996 View MSA. No confident structure predictions are available.
    3 View Details [204..309] deduced N/A No confident structure predictions are available.
    4 View Details [310..352] MSA 1.065996 View MSA. No confident structure predictions are available.
    5 View Details [353..596] PSI-BLAST 50.69897 CDC25b


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle