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Protein Overview: tif452

General Information:
Name(s) found: tif452 / SPBC1709.18 [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • translation initiation factor eIF4E 4F complex subunit [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 243 amino acids

    Gene Ontology:
    Cellular Component: eukaryotic translation initiation factor 4F complex [TASLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: positive regulation of translational initiation [ICLink to PubMed article]
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [ISSLink to PubMed article]
    cellular response to stress [TASLink to PubMed article]
    translational initiation [TASLink to PubMed article]
    Molecular Function: translation initiation factor activity [ISSLink to PubMed article]
    RNA cap binding [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADAEDSRHS KNEGFPNTSL ITEKLDLLDL FGSPKVKTER EGRPARLLEG LSAVNAETAF  60
   61 VKTHPLQHEW TLWFLKPPTQ GLEWSDLLKE IISFKTVEEF WGIFKTISKA SMLPAKSDYS 120
  121 YFLKGIRPEW EDPQNMNGGK WAYQSKHKGS NLDELWLYMV LAAIGETLDP TGKEVTGVVC 180
  181 NMRKGFYRIA VWTRNCNDKD VLEKIGLRFK EVLGISDKET IEYSAHEDSS KAGSMRAKTR 240
  241 MSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..243] PSI-BLAST 59.522879 Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  12.6022960879923 bayes_pls_golite062009
  • RNA cap binding
    		•  8.70938037002519 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  7.91586572659635 bayes_pls_golite062009
  • translation regulator activity
    		•  7.87578736455963 bayes_pls_golite062009
  • RNA binding
    		•  4.72356710460779 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.59281897417644 bayes_pls_golite062009
  • binding
    		•  2.24798267677087 bayes_pls_golite062009
  • protein binding
    		•  0.873044754151905 bayes_pls_golite062009
  • RNA 7-methylguanosine cap binding
    		•  0.544036568660606 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle