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Protein Overview: tif35

General Information:
Name(s) found: tif35 / SPBC18H10.03 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • translation initiation factor eIF3g [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 282 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    eukaryotic 43S preinitiation complex [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    eukaryotic translation initiation factor 3 complex [ISSLink to PubMed article]
    Biological Process: positive regulation of translational initiation [ICLink to PubMed article]
    translational initiation [ISSLink to PubMed article]
    Molecular Function: translation initiation factor activity [ISSLink to PubMed article]
    RNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSKSLDWA DDEDYGTGLP SIQTFDNPDG TKTMIEFRID DNGKKVKVTR VIRKTVITER  60
   61 VQHAVAERKK WKKFGKEAGK NSGVDARTTS VGENVQLRLQ LGWTTTKEEE QDEAALAAAK 120
  121 VKAKGSSVVR CRACKGNHFT AQCPYKSIIG PVDEPPLDAS PVSSRASGAL GEKGRYIAPH 180
  181 LRAGSGRESG DSMFKRERDD SATLRVTNLS DDTREEELRD LFRRFGGIQR VYLAKDKETG 240
  241 RAKGFAFVSY YDRDCAIKAR DRLDGYGWNN LILRCEFSKP RD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..90] deduced N/A No confident structure predictions are available.
    2 View Details [91..282] PSI-BLAST 34.221849 HNRNP A1 (RBD1,2) FROM HOMO SAPIENS

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • RNA binding
    		•  4.50438526063124 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.90076005245206 bayes_pls_golite062009
  • binding
    		•  3.49612884560266 bayes_pls_golite062009
  • translation initiation factor activity
    		•  3.27900316559423 bayes_pls_golite062009
  • mRNA binding
    		•  2.92795844574986 bayes_pls_golite062009
  • structural molecule activity
    		•  2.78501986457503 bayes_pls_golite062009
    		• 1.49431666307335 bayes_pls_golite062009
  • protein binding
    		•  1.32954276279597 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.90573796517364 bayes_pls_golite062009
  • RNA cap binding
    		•  0.847034036194541 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.837097200210041 bayes_pls_golite062009
  • DNA binding
    		•  0.828908978889027 bayes_pls_golite062009
  • translation regulator activity
    		•  0.38120065819101 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.32812362201346 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.128616879457381 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle