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Protein Overview: hob1

General Information:
Name(s) found: hob1 / SPBC21D10.12 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • BAR adaptor protein Hob1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 466 amino acids

    Gene Ontology:
    Cellular Component: medial cortex [TASLink to PubMed article]
    cell cortex of cell tip [TASLink to PubMed article]
    Biological Process: chromatin silencing at centromere [IMPLink to PubMed article]
    establishment or maintenance of cell polarity [IGILink to PubMed article]
    cellular response to stress [IMPLink to PubMed article]
    telomere maintenance [IGILink to PubMed article][IMPLink to PubMed article]
    response to DNA damage stimulus [IGILink to PubMed article]
    chromatin silencing at telomere [IMPLink to PubMed article]
    regulation of mitotic cell cycle [IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    GTPase binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWKGFTKAL ARTPQTLRSK FNVGEITKDP IYEDAGRRFK SLETEAKKLA EDAKKYTDAI  60
   61 NGLLNHQIGF ADACIEIYKP ISGRASDPES YEQEGNAEGI EAAEAYKEIV YDLQKNLASE 120
  121 MDVINTRIVN PTGELLKIVK DVDKLLLKRD HKQLDYDRHR SSFKKLQEKK DKSLKDEKKL 180
  181 YEAETAFEQS SQEYEYYNEM LKEELPKLFA LAQSFIAPLF QGFYYMQLNV YYVLYEKMSH 240
  241 CEIQYFDFNT DILESYERRR GDVKDRAEAL TITKFKTAKP TYKRPGMGPG GKDATASSSS 300
  301 SFSSKREEAA AEPSSSTATD IPPPYSTPSV AGASDYSTPS AGYQTVQTTT TTTEAAAAQY 360
  361 PQAAFPPPPV MPQPAAAAVT TPVAAPVAAA AAAVPVPPPA PAPAAAPAAE HVVALYDYAA 420
  421 QAAGDLSFHA GDRIEVVSRT DNQNEWWIGR LNGAQGQFPG NYVQLE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..244] PSI-BLAST 23.522879 No description for 2ficA was found.
    2 View Details [245..405] FFAS03 1.26 No description for 2j63A was found.
    3 View Details [406..466] PSI-BLAST 19.39794 Crystal structure of the SH3 domain from a S. cerevisiae hypothetical 40.4 kDa protein at 1.39 A resolution

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • actin binding
    		•  4.94949685871786 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  4.41722924924158 bayes_pls_golite062009
  • actin filament binding
    		•  3.69427077755816 bayes_pls_golite062009
  • binding
    		•  2.63972476345585 bayes_pls_golite062009
  • protein binding
    		•  2.08632303609243 bayes_pls_golite062009
  • structural constituent of muscle
    		•  1.44117328570973 bayes_pls_golite062009
  • structural molecule activity
    		•  0.423179340849406 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.371928447183203 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle