YRC Public Data Repository - Protein Structure Prediction

Protein:	hob1
Organism:	Schizosaccharomyces pombe
Length:	466 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hob1.

Description	E-value	Query Range	Subject Range
RV167_CANAL - Regulator of cytoskeleton and endocytosis RVS167 OS=Candida albicans (strain SC5314 / ATCC MYA-2876)... orf19.8807, orf1... - RVS167 CGDID:CAL0002827 Assembly 19, Contig19-10101 (15383, 16807) CDS, translated using codon table...	206.0	[0..1]	[465..35]
gi\|50426917, gi\|... - gi\|50426917\|ref\|XP_462059.1\| hypothetical protein DEHA0G12903g [Debaryomyces hansenii CBS767], gi\|49...	204.0	[0..1]	[465..1]
gi\|28920582, gi\|... - gi\|32406760\|ref\|XP_323993.1\| hypothetical protein [Neurospora crassa], gi\|28920582\|gb\|EAA29944.1\| Am... gi\|85092006 - gi\|85092006\|ref\|XP_959180.1\| Amphiphysin-like, reduced viability upon starvation protein rvs167p [Ne...	200.0	[0..13]	[465..232]
RVS167 - Actin-associated protein, interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and vi... RV167_YEAST - Reduced viability upon starvation protein 167 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288... gi\|190404674 - gi\|190404674\|gb\|EDV07941.1\| cytoskeletal protein [Saccharomyces cerevisiae RM11-1a]	199.0	[0..1]	[465..1]
gi\|21622304 - gi\|21622304\|emb\|CAD37007.1\| probable RVS167 protein [Neurospora crassa]	197.0	[0..1]	[459..1]
gi\|50294009, gi\|... - gi\|50294009\|ref\|XP_449416.1\| hypothetical protein CAGL0M01650g [Candida glabrata CBS138], gi\|4952873... gi\|49528730 - gi\|49528730\|emb\|CAG62392.1\| unnamed protein product [Candida glabrata]	186.0	[0..1]	[465..1]
gi\|42547521, gi\|... - gi\|46137065\|ref\|XP_390224.1\| hypothetical protein FG10048.1 [Gibberella zeae PH-1], gi\|42547521\|gb\|E...	180.0	[0..1]	[465..1]
gi\|119615693, gi... - gi\|3064259\|gb\|AAC39712.1\| amphiphysin IIc2 [Homo sapiens], gi\|21536413\|ref\|NP_647599.1\| bridging int...	180.0	[0..4]	[464..16]
gi\|90305134, gi\|... - gi\|90305134\|gb\|EAS34765.1\| hypothetical protein CIMG_00119 [Coccidioides immitis RS], gi\|119191484\|r...	174.0	[0..1]	[464..1]
gi\|49643218, gi\|... - gi\|50308165\|ref\|XP_454083.1\| unnamed protein product [Kluyveromyces lactis], gi\|49643218\|emb\|CAG9917... gi\|49643218\|emb\|... - unnamed protein product [Kluyveromyces lactis NRRL Y-1140]	170.0	[0..1]	[465..1]

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Predicted Domain #1

Region A:
Residues: [1-244]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWKGFTKAL ARTPQTLRSK FNVGEITKDP IYEDAGRRFK SLETEAKKLA EDAKKYTDAI  60
   61 NGLLNHQIGF ADACIEIYKP ISGRASDPES YEQEGNAEGI EAAEAYKEIV YDLQKNLASE 120
  121 MDVINTRIVN PTGELLKIVK DVDKLLLKRD HKQLDYDRHR SSFKKLQEKK DKSLKDEKKL 180
  181 YEAETAFEQS SQEYEYYNEM LKEELPKLFA LAQSFIAPLF QGFYYMQLNV YYVLYEKMSH 240
  241 CEIQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.522879
Match:	2ficA
Description:	No description for 2ficA was found.

Predicted Domain #2

Region A:
Residues: [245-405]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YFDFNTDILE SYERRRGDVK DRAEALTITK FKTAKPTYKR PGMGPGGKDA TASSSSSFSS  60
   61 KREEAAAEPS SSTATDIPPP YSTPSVAGAS DYSTPSAGYQ TVQTTTTTTE AAAAQYPQAA 120
  121 FPPPPVMPQP AAAAVTTPVA APVAAAAAAV PVPPPAPAPA A

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.26
Match:	2j63A
Description:	No description for 2j63A was found.

Predicted Domain #3

Region A:
Residues: [406-466]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APAAEHVVAL YDYAAQAAGD LSFHAGDRIE VVSRTDNQNE WWIGRLNGAQ GQFPGNYVQL  60
   61 E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.39794
Match:	1ootA
Description:	Crystal structure of the SH3 domain from a S. cerevisiae hypothetical 40.4 kDa protein at 1.39 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	4.94949685871786	bayes_pls_golite062009
cytoskeletal protein binding	4.41722924924158	bayes_pls_golite062009
actin filament binding	3.69427077755816	bayes_pls_golite062009
binding	2.63972476345585	bayes_pls_golite062009
protein binding	2.08632303609243	bayes_pls_golite062009
structural constituent of muscle	1.44117328570973	bayes_pls_golite062009
structural molecule activity	0.423179340849406	bayes_pls_golite062009
structural constituent of cytoskeleton	0.371928447183203	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: