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Protein Overview: his3

General Information:
Name(s) found: his3 / SPBC11B10.02c [Sanger Pombe]
Description(s) found:
Found 24 descriptions.
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  • histidinol-phosphate aminotransferase imidazole acetol phosphate transaminase His3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 384 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: histidine biosynthetic process [TASLink to PubMed article]
    response to nickel ion [IMPLink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEA]
    histidinol-phosphate transaminase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDLNTCLRK NILELQPYRC ARDDFSEGVL LDANECAYGS VISVDGVEFN RYPDPRQIEV  60
   61 KQRLCDLRNK ELSITKPLTP DNICMGVGSD EIIDSLIRIS CIPGKDKILM CPPSYGMYTV 120
  121 SAKINDVEVV KVLLEPDFNL NVDAICETLS KDSAIKVFFA CSPGNPTAKA LKLEDIKKIL 180
  181 EHPTWNGIVV VDEAYIDFSA PDMSALTLVN EYPNLAVCQT LSKSFGLAGI RIGFCLTSKP 240
  241 IATIMNSLKA PYNISEPTSR LALDALSPQS IDKMHTYRDA IIQQRVRLCK ELTTIKGMGK 300
  301 IIGGYDANFI LIQVLDRPEG GKPSNDAAKY LYLQMATMHK VVVRFRGTEP LCEGALRITV 360
  361 GTEEENTILL KTIKLVLQEY YTKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..384] PSI-BLAST 54.30103 Histidinol-phosphate aminotransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • transferase activity
    		•  1.44093490824786 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • histidinol-phosphate transaminase activity
    		•  1.26617748508821 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  0.81652984148807 bayes_pls_golite062009
  • 5-aminolevulinate synthase activity
    		•  0.802089219704558 bayes_pls_golite062009
  • intramolecular transferase activity, transferring amino groups
    		•  0.659071155545801 bayes_pls_golite062009
  • binding
    		•  0.536634592992536 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.013097682076602 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle