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Protein Overview: his1

General Information:
Name(s) found: his1 / SPAC25G10.05c [Sanger Pombe]
Description(s) found:
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  • gi|729716|sp|P40373.1|HIS1_SCHPO RecName: Full=ATP phosphoribosyltransferase; Short=ATP-PRTase; Short=ATP-PRT [NCBI NR]
  • gi|476140|gb|AAA92790.1| ATP phosphoribosyltransferase [NCBI NR]
  • pir||S55076 ATP phosphoribosyltransferase (EC 2.4.2.17) - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19115437|ref|NP_594525.1| ATP phosphoribosyltransferase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1256528|emb|CAA94634.1| ATP phosphoribosyltransferase [Schizosaccharomyces pombe] [NCBI NR]
  • ATP phosphoribosyltransferase [Sanger Pombe]
  • ATP phosphoribosyltransferase OS=Schizosaccharomyces pombe GN=his1 PE=2 SV=1 [Swiss-Prot]
  • ATP PHOSPHORIBOSYLTRANSFERASE; FIRST STEP IN HISTIDINE BIOSYNTHESIS PATHWAY; SIMILAR TO S. CEREVISIAE HIS1: P40373; [pompepVF.fasta]
  • ATP phosphoribosyltransferase (EC 2.4.2.17) [pompep4896]
  • |his1||ATP phosphoribosyltransferase (PMID 7732725) [pompepnew.fasta]
  • ATP phosphoribosyltransferase (EC 2.4.2.17) (ATP-PRTase) (ATP-PRT) [4896.FASTAC]
  • |his1||ATP phosphoribosyltransferase (PMID 7732725)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • |his1||ATP phosphoribosyltransferase |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • atp phosphoribosyltransferase [Schizosaccharomyces pombe]gi|1256528|emb|CAA94634.1| his1 [Schizosaccharomyces pombe]gi|729716|sp|P40373|HIS1_SCHPO ATP phosphoribosyltransferase (ATP-PRTase) (ATP-PRT)gi|476140|gb|AAA92790.1| ATP phosphoribosyltransferas [nrdb_11152004_Chlamydomonas]
  • (P40373) ATP phosphoribosyltransferase (EC 2.4.2.17) [pompep4896_normal_reversed]
  • |his1||ATP phosphoribosyltransferase|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • ATP phosphoribosyltransferase (ATP-PRTase) (ATP-PRT) [nr-271106-contam.fasta]
  • SPAC25G10.05c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC25G10.05c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • ATP phosphoribosyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=his1 PE=2 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 310 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: histidine biosynthetic process [ICLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    ATP binding [IEA]
    ATP phosphoribosyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLVNHLEDR LLFAVPKKGR LYESCVNVLK GSDIKFRRNP RLDIALVQNL PIALVFLPAA  60
   61 DIPRFVGTGR VHLGITGQDQ IAEARLRIGD KLKIEELVDL QFGGCKLQVQ VPESGDITSV 120
  121 DQLVGRRIVT SFEYLVAEYF DKVEKKAKSE GKVDSGIKTE ISFVSGSVEA SCALGIADAV 180
  181 VDLVESGETM RASGLKPIET VMSTSAVLVR SSNCSSELEP LLQTIITRIR GYIIAQQYVL 240
  241 VNYNVNREHL PVVLKITPGK RAPTITTLDE PGWVAVSSMV VKKEVAQVMD KLSQNHAHDI 300
  301 LVLSIDNSRP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..310] PSI-BLAST 103.0 STRUCTURE OF THE E.COLI ATP-PHOSPHORIBOSYLTRANSFERASE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ATP phosphoribosyltransferase activity
    		•  1.91045033958508 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.411352163551675 bayes_pls_golite062009
  • transcription factor activity
    		•  0.388220094901111 bayes_pls_golite062009
  • DNA binding
    		•  0.381460145340259 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.264041862712904 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  0.136083454159139 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle