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Protein Overview: gsa1

General Information:
Name(s) found: gsa1 / SPAC3F10.04 [Sanger Pombe]
Description(s) found:
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  • pir||T38705 glutathione synthetase large chain - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19114848|ref|NP_593936.1| glutathione synthetase large subunit Gsa1 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|1708058|sp|P35669.2|GSHB_SCHPO RecName: Full=Glutathione synthetase large chain; AltName: Full=Glutathione synthase large chain; AltName: Full=GSH synthetase large chain; Short=GSH-S; AltName: Full=Phytochelatin synthetase [NCBI NR]
  • gi|1617215|emb|CAA69691.1| phytochelatin-synthetase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1182051|emb|CAA93302.1| glutathione synthetase large subunit Gsa1 [Schizosaccharomyces pombe] [NCBI NR]
  • glutathione synthetase large subunit Gsa1 [Sanger Pombe]
  • Glutathione synthetase large chain OS=Schizosaccharomyces pombe GN=gsa1 PE=1 SV=2 [Swiss-Prot]
  • GLUTATHIONE SYNTHETASE LARGE CHAIN: P35669; [pompepVF.fasta]
  • Glutathione synthetase large chain (EC 6.3.2.3) (Glutathione synthase large chain) (GSH synthetase large chain) (GSH-S) (Phytochelatin synthetase) [pompep4896]
  • |gsa1|gsh2|glutathione synthetase large chain (PMID 8914526) [pompepnew.fasta]
  • |gsa1|gsh2|glutathione synthetase (large subunit) (PMID 8914526)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • glutathione synthetase large chain [Schizosaccharomyces pombe]gi|1617215|emb|CAA69691.1| phytochelatin-synthetase [Schizosaccharomyces pombe]gi|1182051|emb|CAA93302.1| gsa1 [Schizosaccharomyces pombe]gi|7490593|pir||T38705 glutathione synthetase large [nrdb_11152004_Chlamydomonas]
  • |gsa1|gsh2|glutathione synthetase |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (P35669) Glutathione synthetase large chain (EC 6.3.2.3) (Glutathione synthase large chain) (GSH synthetase large chain) (GSH-S) (Phytochelatin synthetase) [pompep4896_normal_reversed]
  • |gsa1|gsh2|glutathione synthetase large subunit Gsa1|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPAC3F10.04 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Glutathione synthetase large chain (Glutathione synthase large chain) (GSH synthetase large chain) (GSH-S) (Phytochelatin synthetase) [nr-271106-contam.fasta]
  • phytochelatin-synthetase [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • SPAC3F10.04 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Glutathione synthetase large chain OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gsa1 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 498 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: phytochelatin biosynthetic process [IMPLink to PubMed article]
    glutathione biosynthetic process [ICLink to PubMed article]
    cellular response to stress [TASLink to PubMed article]
    response to cadmium ion [IMPLink to PubMed article]
    Molecular Function: magnesium ion binding [ISS]
    ATP binding [IEA]
    protein homodimerization activity [ISS]
    glutathione binding [ISS]
    glutathione synthase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIEKYTPEQ IEELGKGARD FAFAHGVVFT ELSVSKEGRN IATQIPITLF PSVIPHGAFV  60
   61 EAVSVQKAYN KLYAKIANDY EFLRLHLQSI TKYDEFMNKL WNLYQKHREA VAHLKENQFQ 120
  121 PLSLGVFRSD YMVHQDDSFI GCKQVEFNTI SVSFGGVSKA VSNLHAYCSQ SGLYRKPLTT 180
  181 NYLTVNTSVS GICTGISNAV DAYRDYVKNI TSKMNIASDN TKPIVLFVVK GGERNITDQR 240
  241 TLEYELLNRF HVISKRIDIA ELNSLIHDKS SNKLYMKTSF TTYEVAVVYY RVGYALDDYP 300
  301 SQEAWDMRLT IENTLAIKCP SISTHLAGSK KIQQVLAESN ALERFLEGDE LQAVRSTFAD 360
  361 MYPLDDTPRG KEGIKLAFEK PEDFVLKPQR EGGGNNTYGK DIPGLLSKMP QEEWDSYILM 420
  421 RYINAVPSQN YILKGERPEK FDVVDEIGIL GTIVWNIKTD EVVQNGQSGF ICRTKPKKTN 480
  481 EGGVATGYAS LSSIELSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..498] PSI-BLAST 165.0 Eukaryotic glutathione synthetase, substrate-binding domain; Eukaryotic glutathione synthetase ATP-binding domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle