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Protein Overview: SPBPB2B2.12c

General Information:
Name(s) found: SPBPB2B2.12c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • UDP-glucose 4-epimerase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 713 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: carbohydrate metabolic process [IEA]
    cellular response to stress [IEPLink to PubMed article]
    galactose metabolic process [IEA]
    Molecular Function: coenzyme binding [IEA]
    UDP-glucose 4-epimerase activity [IEA]
    aldose 1-epimerase activity [IEA]
    carbohydrate binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVQDEYILV TGGAGYIGSH TVIELINHGY KVIIVDNLCN SCYDAVARVE FIVRKSIKFF  60
   61 KLDLRDKEGL AQIFDTFKIK GVIHFAALKA VGESMKLPLE YYDNNICGTI TLLNVMREHR 120
  121 VKTVVFSSSA TVYGDATRFD NMIPIPESCP NDPTNPYGKT KYAIENIIKD LHTSDNTWRG 180
  181 AILRYFNPIG AHPSGLLGED PLGIPNNLLP FLAQVAIGRR EKLLVFGDDY DSHDGTPIRD 240
  241 YIHVVDLAKG HIAALNYLNK INNSEGMYRE WNLGTGKGSS VFDIYHAFCK EVGKDLPYEV 300
  301 VGRRTGDVLN LTASPNRANS ELKWKAELSI TDACRDLWKW TIENPFGFQI DNYKWKLFNT 360
  361 LGIMDYKNRL HTICFQDLEV SIANYGALVQ AVRYKGRNLV NGFNDFSRYK LKENPFFGAT 420
  421 IGRFANRIAN GQFEVDGHLY TLCKNENNKT TLHGGNNGFD KQFFLGPIAR QYEDYNTLEF 480
  481 ILVDKDGNNG FPSDLETLVK YTIKNNSLEI EYKSVIPEYS KLNVTAVNLT NHSYWNLASP 540
  541 NKTIDGTIIK STTNVYLKVN SETSLPTGDI VEWQNDITKP TKLDPNISFD NCFIVDREAS 600
  601 KFCLDTRKYS LKNIVEVIHP SVPVKLVVST TEPAFQLYTG DGNDICEFQS RSGFCVETGR 660
  661 FINALNNEKW SKQVILRKGE VYGARSKFSL YAQDLEENKH FLDSASYNSG EYY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..713] PSI-BLAST 171.0 Crystal structure of the gal10 fusion protein galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae complexed with NAD, UDP-glucose, and galactose

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • aldose 1-epimerase activity
    		•  2.85100059704396 bayes_pls_golite062009
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.868888700854563 bayes_pls_golite062009
  • binding
    		•  0.835119783772935 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • DNA binding
    		•  0.790382977752475 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  0.65743456407889 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.613310508772122 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  0.48941662111046 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.44922383360529 bayes_pls_golite062009
  • coenzyme binding
    		•  0.35922330382799 bayes_pls_golite062009
  • transcription factor activity
    		•  0.11102650759187 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  0.0498966688564807 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle