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Protein Overview: fus1

General Information:
Name(s) found: fus1 / SPAC20G4.02c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • formin Fus1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1372 amino acids

    Gene Ontology:
    Cellular Component: cell division site [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed articleLink to PubMed article]
    mating projection [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: plasma membrane fusion during cytogamy [IMPLink to PubMed article]
    cellular response to stress [IEPLink to PubMed article]
    actin cytoskeleton organization [ISSLink to PubMed article]
    actin filament bundle assembly [NASLink to PubMed article]
    Molecular Function: actin binding [ISSLink to PubMed article]
    SH3 domain binding [IEA]
    Rho GTPase binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMTASFKGIR ISKPIVKEIS SFGSLTNIDL HTDPYEKVEA KALSRSRLKN QSVKKTDLRI  60
   61 TNDYSSLFVS IENKKNTIPD IHCNNLSKRP VGFTDSYVPG EALLCPDDPN LVNELFDDVL 120
  121 KRLREEKSDS GEQFHWDANV TLSQENKWSF ITGYLSRNDK FLKISSNDSE LNVKASVISY 180
  181 IEKLSCTPLK LKYVESLAVA LRTESVTWVR YFLLMGGHIV LAKILQAIHE KKHLKSPDIT 240
  241 LEIAILKSMR CIIGQKIGTD FYLSNKYPID SVVHCLLSTK LLVRKLAAEL LTFLCYSEKP 300
  301 NGINAIMKCM KNFANLKVES MNVFDLWLSQ WKRTLLEKVV TEEKKVLEEA ALHDKITIEY 360
  361 IISQMLLINA FLENIPSKTA LLQFKESLRI GNFKSILLIL KKINDEGVLK QLEKCVKLVS 420
  421 LDTANEKHFL KHTPNSAAHQ SLLNTNMFND ANFEFMVKEH IKNFLKLLKE HNNPVRIIKL 480
  481 LDCLVLTLQA DKGNGNSNND IDCFYKELKI GNEQGNNAPG YSSVTSGYGT TNSKKVVASY 540
  541 DNTDDNEYSV SKSELYATGD TNNTTNQGYE NSERKYVESS KYETDLKNIF DCLCLLFPSE 600
  601 FDPQSSFSAE KIFSKLKHLL TRTRDSYISE DTKILRLLNR SSSKLQDRDQ EYLISKNNVN 660
  661 GNGNRDWVQP VNTTSSVSAF ASPRIKPKLL FQPNQDEKLK LCKLDLAKAN SITLKSEPSS 720
  721 AVSTHSFEVH LSMPGTQIKS ANLAEKMETS KHKVFNPKRI DVVSDLPLDY RKSYYGRFSI 780
  781 TDTKRFSKIE NMRIKEVIDG NPFKAPPPAP LPPPAPPLPT AMSSLQKFEK NDSQIFRKTI 840
  841 IIPENISIDD IFKFCSGSES EVYASKIPGE LCNPSKRLKQ LHWKRLEVPF EKTLWNIVVA 900
  901 DPYLLTLKLT AEGIFKQLED CYPLREVTVS NKKVKEYTGF MPVDLQQMVS IRLHRFNSLT 960
  961 PIEIAKKFFH CDHDIMELVD FFNDRKFFRQ EGLKKQLKPY MSSRNEEVME VSEKLLELSR1020
 1021 FDQIYTLIVV DIDTYYEKRM AALKIKSFLA NNFRDFRRQI RKLHCASLEL KSSLHFKYFL1080
 1081 NLVLHIGNFM NDAPRRAKGY RLESLLRASM IKNDKTGLTL LHTIEKIVRT HFPQLEAFLV1140
 1141 DLKAIPEISR FNLEQLEQDC NDICERMKNV EKDFSNEGIF SNHKALHPDD HICEVMVPWI1200
 1201 PSGKSMVDEL NSDITELKTT LKTTLLMYGE NPDEPTSSAR FFNNLNEIIL EYKKASTVNQ1260
 1261 KMEKEEELAF LRLQALKASV KSNNAENSGS SKNEEVSATM ENLISQLQKG LCDDSLSNKT1320
 1321 DCTESSKQTI ETLMNYENDK QTLEGSNKKR QTVVLKAECM LKQLENNNEL KR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..94] deduced N/A No confident structure predictions are available.
    2 View Details [95..571] PSI-BLAST 77.522879 Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP
    3 View Details [572..642] deduced N/A No confident structure predictions are available.
    4 View Details [643..848] MSA 3.307994 View MSA. No confident structure predictions are available.
    5 View Details [849..1282] PSI-BLAST 38.39794 Bni1p Formin Homology 2 Domain complexed with ATP-actin
    6 View Details [1283..1372] PSI-BLAST 5.09691 Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain; Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.27902748675387 bayes_pls_golite062009
  • protein binding
    		•  1.94427330399472 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.79889605917047 bayes_pls_golite062009
  • actin binding
    		•  1.58742487047757 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle