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Protein Overview: SPCC1183.03c

General Information:
Name(s) found: SPCC1183.03c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • frataxin homolog [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 158 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: cellular iron ion homeostasis [ISSLink to PubMed article]
    oxygen and reactive oxygen species metabolic process [ISSLink to PubMed article]
    iron incorporation into metallo-sulfur cluster [ISSLink to PubMed article]
    homeostatic process [NAS]
    regulation of catalytic activity [ICLink to PubMed article]
    Molecular Function: iron ion binding [ISSLink to PubMed article]
    enzyme regulator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSLRAAFRR RTPIFLKPYE FSTNVFGLRC RYYSQVRHNG ALTDLEYHRV ADDTLDVLND  60
   61 TFEDLLEEVG KKDYDIQYAN GVITLMLGEK GTYVINKQPP AHQIWLSSPV SGPKHYEYSL 120
  121 KSKTWCSTRD EGTLLGILSS EFSKWFSRPI EFKKSEDF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..158] PSI-BLAST 36.522879 C-terminal domain of frataxin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • iron chaperone activity
    		•  4.16905358201916 bayes_pls_golite062009
  • ferric iron binding
    		•  3.17697632477325 bayes_pls_golite062009
  • iron ion binding
    		•  2.78584553912929 bayes_pls_golite062009
  • 2 iron, 2 sulfur cluster binding
    		•  2.25545886640675 bayes_pls_golite062009
  • transition metal ion binding
    		•  1.85229574432416 bayes_pls_golite062009
  • metal cluster binding
    		•  1.76354337338376 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  1.76354337338376 bayes_pls_golite062009
  • metallochaperone activity
    		•  1.67572555512957 bayes_pls_golite062009
  • ferrous iron binding
    		•  1.61332056179381 bayes_pls_golite062009
  • binding
    		•  1.55331726001774 bayes_pls_golite062009
  • cation binding
    		•  1.42164579673909 bayes_pls_golite062009
  • metal ion binding
    		•  1.42164579673909 bayes_pls_golite062009
  • ion binding
    		•  1.4150396069236 bayes_pls_golite062009
  • protein binding
    		•  0.356112453590986 bayes_pls_golite062009
  • oxidoreductase activity, oxidizing metal ions, oxygen as acceptor
    		•  0.310374472796773 bayes_pls_golite062009
  • ferroxidase activity
    		•  0.310374472796773 bayes_pls_golite062009
  • catalytic activity
    		•  0.276917867171685 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle