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Protein Overview: fps1

General Information:
Name(s) found: fps1 / SPAC6F12.13c [Sanger Pombe]
Description(s) found:
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  • pir||T11664 geranyltranstransferase (EC 2.5.1.10) - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|3287843|sp|O14230.1|FPPS_SCHPO RecName: Full=Farnesyl pyrophosphate synthetase; Short=FPP synthetase; Short=FPS; AltName: Full=Farnesyl diphosphate synthetase; Includes: RecName: Full=Dimethylallyltranstransferase; Includes: RecName: Full=Geranyltranst [NCBI NR]
  • gi|2330860|emb|CAB11097.1| geranyltranstransferase Fps1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114211|ref|NP_593299.1| farnesyl pyrophosphate synthetase [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • geranyltranstransferase Fps1 [Sanger Pombe]
  • Farnesyl pyrophosphate synthase OS=Schizosaccharomyces pombe GN=fps1 PE=1 SV=1 [Swiss-Prot]
  • FARNESYL PYROPHOSPHATE SYNTHETASE: O14230;P78756; [pompepVF.fasta]
  • Probable farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)] [pompep4896]
  • |||putative farnesyl pyrophosphate synthetase [pompepnew.fasta]
  • Probable farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)] [4896.FASTAC]
  • |||farnesyl pyrophosphate synthetase|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • farnesyl pyrophosphate synthetase [Schizosaccharomyces pombe]gi|2330860|emb|CAB11097.1| SPAC6F12.13c [Schizosaccharomyces pombe]gi|7522270|pir||T11664 geranyltranstransferase (EC 2.5.1.10) - fission yeast (Schizosaccharomyces pombe)gi|3287843|sp|O1423 [nrdb_11152004_Chlamydomonas]
  • (O14230) Probable farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10)] [pompep4896_normal_reversed]
  • |fps1||geranyltranstransferase Fps1|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC6F12.13c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC6F12.13c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Probable farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Farnesyl diphosphate synthetase) [Includes: Dimethylallyltranstransferase ; Geranyltranstransferase ] [nr-271106-contam.fasta]
  • Farnesyl pyrophosphate synthase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=fps1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 347 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: ergosterol biosynthetic process [IGILink to PubMed article]
    protein prenylation [ICLink to PubMed article]
    isoprenoid biosynthetic process [ISSLink to PubMed article]
    farnesyl diphosphate biosynthetic process [IGILink to PubMed article]
    Molecular Function: geranyltranstransferase activity [ISSLink to PubMed article]
    magnesium ion binding [IEA]
    protein binding [IPILink to PubMed article]
    dimethylallyltranstransferase activity [IGILink to PubMed article]
    protein farnesyltransferase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAVDKRAKF ESALPVFVDE IVNYLKTINI PDDVTEWYKN SLFHNTLGGK YNRGLSVIDS  60
   61 YEILLGHPLD EAAYMKAAVL GWMVELLQSF FLIADDIMDA SKTRRGQPCW YLMPGVGNIA 120
  121 INDAFMVESA IYFLLKKHFR QESCYVDLIE LFHDVTFQTE LGQQLDLLTA PEDSVDLSKF 180
  181 SLQKHSFIVI YKTAFYSFYL PVALAMHLAG VATPENLKCA QDILIILGKY FQVQDDYLDC 240
  241 YGDPTVTGKI GTDILDNKCS WIINLALAKC TPEQRVILDD NYGRKDSESE KRVKAVFEEL 300
  301 NIRGEFENYE ESEVSEIKKL IDGVDESTGL KKSIFTTFLG KIYKRNK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..347] PSI-BLAST 81.221849 STRUCTURE OF FARNESYL PYROPHOSPHATE SYNTHETASE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • prenyltransferase activity
    		•  8.01554498091556 bayes_pls_golite062009
  • farnesyl-diphosphate farnesyltransferase activity
    		•  5.04441642023356 bayes_pls_golite062009
  • protein prenyltransferase activity
    		•  4.13910090627719 bayes_pls_golite062009
  • geranyltranstransferase activity
    		•  3.86169009960142 bayes_pls_golite062009
  • transferase activity
    		•  3.63071481728466 bayes_pls_golite062009
  • farnesyltranstransferase activity
    		•  3.11591733497708 bayes_pls_golite062009
  • protein farnesyltransferase activity
    		•  2.85107079482202 bayes_pls_golite062009
  • catalytic activity
    		•  2.4040324437254 bayes_pls_golite062009
  • dimethylallyltranstransferase activity
    		•  1.91559289231283 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  1.82540911622956 bayes_pls_golite062009
  • binding
    		•  1.45201203247999 bayes_pls_golite062009
  • protein binding
    		•  0.270583155998354 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.68

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle