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Protein Overview: fnx1

General Information:
Name(s) found: fnx1 / SPBC12C2.13c [Sanger Pombe]
Description(s) found:
Found 15 descriptions.
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  • MFS multidrug efflux transporter [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 531 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole membrane [IDALink to PubMed article]
    integral to vacuolar membrane [IC]
    fungal-type vacuole [IDALink to PubMed article]
    Biological Process: asparagine transport [ICLink to PubMed article]
    lysine transport [ICLink to PubMed article]
    isoleucine transport [ICLink to PubMed article]
    cellular response to stress [IEPLink to PubMed article]
    G1 to G0 transition [IMPLink to PubMed article]
    amino acid import into vacuole [IMPLink to PubMed article]
    Molecular Function: L-lysine transmembrane transporter activity [IMPLink to PubMed article]
    L-isoleucine transmembrane transporter activity [IMPLink to PubMed article]
    L-asparagine transmembrane transporter activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDQVNLATE QTSLLYPEVS RKKEELSVNK WTILPALWVG GFLSALDMTI VASLYPVIGS  60
   61 EFKLMNNASY IVTAYLITNT AFQPLYGRLS DIFGRRPTVV FANAAFTLGT FWCGISRSLP 120
  121 ELCMARALAG IGGGGLGTMS SIISSDIVSL RERGTWQGIT NIVWGIGGSL GGPLGGLIAQ 180
  181 RWGWRTAFHF QVPMGILSTI LVAWRVRVKP TVRNSNASLL SRIDYLGSFL LVTGITALVV 240
  241 TFNMGGDAFP WVSPVIITLL VSSVLILFAF YWVEKNIAVE PIAPVEILSQ PTPLNVCLGN 300
  301 FFNAFCSFVI VYELPLFFET TLLMPSSEAG VRIFPYVIST SVGSLCSGLY MKKTGRYRNL 360
  361 VIAGFFFMLM GIVSFAVLTS FGHRTPLILI SLCLAMTGCS YGMNLTSTLI AIISSLAPEE 420
  421 QAVATGLSYL FRATGSVIGI SLSQTTTLSI LMKQLASNLK DDPDKDDLIR RLRESISIIP 480
  481 NLPKDIQKLV IKSYATAFTW TFALVAIIAF AGFWCSLRIK QFYLHTSVDR S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..531] PSI-BLAST 22.522879 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • binding
    		•  0.794947356296983 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle