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Protein Overview: erg9

General Information:
Name(s) found: erg9 / SPBC646.05c [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • squalene synthase Erg9 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 460 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [IDALink to PubMed article]
    nuclear membrane-endoplasmic reticulum network [IDALink to PubMed article]
    integral to membrane [IEA]
    endoplasmic reticulum [IDALink to PubMed article][IGILink to PubMed article]
    Biological Process: ergosterol biosynthetic process [IGILink to PubMed article]
    isoprenoid biosynthetic process [IEA]
    Molecular Function: magnesium ion binding [IEA]
    protein binding [IPILink to PubMed article]
    farnesyl-diphosphate farnesyltransferase activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLANRIEEI RCLCQYKLWN DLPSYGEDEN VPQNIRRCYQ LLDMTSRSFA VVIKELPNGI  60
   61 REAVMIFYLV LRGLDTVEDD MTLPLDKKLP ILRDFYKTIE VEGWTFNESG PNEKDRQLLV 120
  121 EFDVVIKEYL NLSEGYRNVI SNITKEMGDG MAYYASLAEK NDGFSVETIE DFNKYCHYVA 180
  181 GLVGIGLSRL FAQSKLEDPD LAHSQAISNS LGLFLQKVNI IRDYREDFDD NRHFWPREIW 240
  241 SKYTSSFGDL CLPDNSEKAL ECLSDMTANA LTHATDALVY LSQLKTQEIF NFCAIPQVMA 300
  301 IATLAAVFRN PDVFQTNVKI RKGQAVQIIL HSVNLKNVCD LFLRYTRDIH YKNTPKDPNF 360
  361 LKISIECGKI EQVSESLFPR RFREMYEKAY VSKLSEQKKG NGTQKAILND EQKELYRKDL 420
  421 QKLGISILFV FFIILVCLAV IFYVFNIRIH WSDFKELNLF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..399] PSI-BLAST 85.39794 Squalene synthase
    2 View Details [400..460] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • prenyltransferase activity
    		•  5.34003736022396 bayes_pls_golite062009
  • farnesyl-diphosphate farnesyltransferase activity
    		•  5.04441642023356 bayes_pls_golite062009
  • geranyltranstransferase activity
    		•  3.86169009960142 bayes_pls_golite062009
  • farnesyltranstransferase activity
    		•  3.11591733497708 bayes_pls_golite062009
  • catalytic activity
    		•  2.4040324437254 bayes_pls_golite062009
  • dimethylallyltranstransferase activity
    		•  1.91559289231283 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  1.82540911622956 bayes_pls_golite062009
  • transferase activity
    		•  1.77738506203957 bayes_pls_golite062009
  • binding
    		•  0.0206192709356209 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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