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Protein Overview: SPAC20G8.04c

General Information:
Name(s) found: SPAC20G8.04c [Sanger Pombe]
Description(s) found:
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  • pir||T38126 probable electron transfer flavoprotein precursor - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|2829736|sp|P87111.1|ETFD_SCHPO RecName: Full=Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Short=ETF-ubiquinone oxidoreductase; Short=ETF-QO; AltName: Full=Electron-transferring-flavoprotein dehydrogenase; Short=ETF [NCBI NR]
  • gi|2094859|emb|CAB08598.1| mitochondrial electron transfer flavoprotein-ubiquinone oxidoreductase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114233|ref|NP_593321.1| electron transfer flavoprotein-ubiquinone oxidoreductase [Schizosaccharomyces pombe] [NCBI NR]
  • mitochondrial electron transfer flavoprotein-ubiquinone oxidoreductase [Sanger Pombe]
  • Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Schizosaccharomyces pombe GN=SPAC20G8.04c PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE ELECTRON TRANSFER FLAVOPROTEIN- UBIQUINONE OXIDOREDUCTASE: P87111; [pompepVF.fasta]
  • PUTATIVE ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE PRECURSOR: P87111; [pompepV13]
  • Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring-flavoprotein dehydrogenase) [pompep4896]
  • |||putative electron transfer flavoprotein-ubiquinone oxidoreductase [pompepnew.fasta]
  • |||electron transfer flavoprotein-ubiquinone oxidoreductase (predicted)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative electron transfer flavoprotein-ubiquinone oxidoreductase [Schizosaccharomyces pombe]gi|2094859|emb|CAB08598.1| SPAC20G8.04c [Schizosaccharomyces pombe]gi|7492555|pir||T38126 probable electron transfer flavoprotein precursor - fission yeast (Sch [nrdb_11152004_Chlamydomonas]
  • |||electron transfer flavoprotein-ubiquinone oxidoreductase|Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (P87111) Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (EC 1.5.5.1) (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring-flavoprotein dehydrogenase) [pompep4896_normal_reversed]
  • |||mitochondrial electron transfer flavoprotein-ubiquinone oxidoreductase|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor (ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring-flavoprotein dehydrogenase) [nr-271106-contam.fasta]
  • SPAC20G8.04c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC20G8.04c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |||mitochondrial electron transfer flavoprotein-ubiquinone oxidoreductase |Schizosaccharomyces pombe|chr 1|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC20G8.04c PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 632 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [ISSLink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: NADH oxidation [ISSLink to PubMed article]
    thiamin biosynthetic process [IEA]
    Molecular Function: iron ion binding [IEA]
    electron-transferring-flavoprotein dehydrogenase activity [ISSLink to PubMed article]
    4 iron, 4 sulfur cluster binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYLSRSALA RSVGAKHLTG VLRKIGRRGG RSMHVLPLAS PSTLLKISSQ TLRQDFTVLG  60
   61 ARNFHSSSVR LNELTDNLRK LDTIEREVED VDVCIVGAGP AGLSAAIRIK QQAAKANRDI 120
  121 RVVVLEKAAE PGNHSVSGAV IQPTALDELL PNWRDDPPEN CTAVTHDKMK FLIPKLHFPI 180
  181 PVPPAMKNHG NYVMSLAEFT RWLAAKAEEY GVEIYPSFAA SEVLYNKDGS VIGVATNDFG 240
  241 VDSKGLPKDN FERGMAFHAP VTLFAEGAHG SLSKSIIKRF NLRGNCEPQT YGLGVKEVWR 300
  301 VPDENFRKGE VAHTLGWPMR NDTYGGGFMY QFGDNYVTVG LVVGLDYPNP YVSPALEFQR 360
  361 MKQNPFFAKV LKGGKCLEYA ARALNEGGYQ AIPKLVFPGG ALIGCSAGFV NVAKIKGTHT 420
  421 AMKSGIVAAD AIVDAFGRDA ASKPLLLNDY EENLKNTYVF KELYSVRNIR PSFHSFLGNY 480
  481 GGMAYSAVEA YVLKGRVPWT LKHKGGDAKA TKSASKYKPI NYPKPDNVLS FDIPTSVSRS 540
  541 ATMHAENQPC HLFDHRPKDR KSCFETYKGV ENKFCPAGVY EYVNDEASSY GKRFVINSQN 600
  601 CVHCKTCDIK DPLQGIQWKT PQGGDGPKYT LT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..632] PSI-BLAST 116.0 No description for 2gmhA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  6.5929955386305 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  6.45562261241375 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  6.34963309803617 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  5.69483449389334 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  3.91001933271643 bayes_pls_golite062009
  • electron carrier activity
    		•  3.21957528314564 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  3.11137503143637 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.10483430063263 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.04960158864768 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor
    		•  3.0400550620086 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.87261684242536 bayes_pls_golite062009
  • formate dehydrogenase activity
    		•  2.79579164562277 bayes_pls_golite062009
  • electron-transferring-flavoprotein dehydrogenase activity
    		•  2.1276770745496 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
    		•  1.45104542724719 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors
    		•  1.35744482443829 bayes_pls_golite062009
  • transporter activity
    		•  1.2818063852101 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
    		•  1.08975609376408 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.07293152484928 bayes_pls_golite062009
  • binding
    		•  0.850925220183928 bayes_pls_golite062009
  • dihydrolipoyl dehydrogenase activity
    		•  0.69501605197281 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.556967966402473 bayes_pls_golite062009
  • catalytic activity
    		•  0.488483980994331 bayes_pls_golite062009
  • metal cluster binding
    		•  0.484911132627709 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  0.484911132627709 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.31459693204333 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.301257942260531 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.162130833238942 bayes_pls_golite062009
  • protein binding
    		•  0.122045589752402 bayes_pls_golite062009
  • NADPH-adrenodoxin reductase activity
    		•  0.10059033442163 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.0827182678048914 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.0724852054074128 bayes_pls_golite062009
  • DNA binding
    		•  0.022476246602636 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.72

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle