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Protein Overview: eso1

General Information:
Name(s) found: eso1 / SPBC16A3.11 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • sister chromatid cohesion protein Eso1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 872 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [IC]
    Biological Process: DNA repair [ISSLink to PubMed article]
    regulation of maintenance of mitotic sister chromatid cohesion [TASLink to PubMed article]
    DNA-dependent DNA replication [IMPLink to PubMed article]
    establishment of mitotic sister chromatid cohesion [IMPLink to PubMed article]
    protein amino acid acetylation [ICLink to PubMed article]
    fear response [IC]
    translesion synthesis [ISSLink to PubMed article]
    Molecular Function: DNA-directed DNA polymerase activity [ISSLink to PubMed article]
    zinc ion binding [IEA]
    protein binding [IPILink to PubMed article]
    acyltransferase activity [ISSLink to PubMed article]
    damaged DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELGKSKFSW KDLQYCDKAG TQNSPLRVVA HIDQDAFYAQ VESVRLGLDH SVPLAVQQWQ  60
   61 GLIAVNYAAR AANISRHETV TEAKKKCPEL CTAHVKTWKA GESEAKYHEN PNPNYYKTCL 120
  121 DPYRHESVKI LNIIKKHAPV VKKASIDECF IELTSDVKRI VLEEYPYLKI PSEDSNVALP 180
  181 QAPVLLWPAE FGMVIEEEVV DRTKEDYERD WDDVFLFYAA KIVKEIRDDI YLQLKYTCSA 240
  241 GVSFNPMLSK LVSSRNKPNK QTILTKNAIQ DYLVSLKITD IRMLGGKFGE EIINLLGTDS 300
  301 IKDVWNMSMD FLIDKLGQTN GPLVWNLCHG IDNTEITTQV QIKSMLSAKN FSQQKVKSEE 360
  361 DAINWFQVFA SDLRSRFLEL EGMRRPKTIC LTVVSRFLRK SRSSQIPMNV DISTQFIVEA 420
  421 TSKLLRQLQQ EFDVYPISNL SISFQNIIEV DRNSRGIEGF LKKSNDEIYM STSVSPSIEG 480
  481 RAKLLNENMR ENNSFELSSE KDIKSPKRLK RGKGKGIFDM LQQTAVSKPT ENSADETYTC 540
  541 EECEQKITLS ERNEHEDYHI ALSISRKERY NNLVPPSHDK PKQVKPKTYG RKTGSKHYAP 600
  601 LSDETNNKRA FLDAFLGNGG NLTPNWKKQT PKAISNSSDN MTQLHLDLAN STVTCSECSM 660
  661 EYNSTSEEDI LLHSRFHSRV LGGVTVSFQC SPIYRVNYGL SSDCIYSINS ESSLIDQRKA 720
  721 EEALSFVNNE LSSEPIETIG VDKYTTFLFI SDKKCVGLLL AERISSAYIV DELELNNNNS 780
  781 TSSAVYIKNE NLRKGFVLGI SRIWVSASRR KQGIASLLLD NALKKFIYGY VISPAEVAFS 840
  841 QPSESGKQFI ISWHRSRNNG SSKSLRYAVY ES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..508] PSI-BLAST 71.0 DNA polymerase eta
    2 View Details [509..703] FFAS03 2.42 No description for 2i13A was found.
    3 View Details [704..872] MSA 3.060963 View MSA. Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA-directed DNA polymerase activity
    		•  9.12112857204028 bayes_pls_golite062009
  • DNA polymerase activity
    		•  9.07163148377911 bayes_pls_golite062009
  • DNA primase activity
    		•  6.94812039437428 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  4.75943480079119 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.94496917620645 bayes_pls_golite062009
  • DNA binding
    		•  2.53092801704688 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.33765586478028 bayes_pls_golite062009
  • transferase activity
    		•  1.93427633579563 bayes_pls_golite062009
  • binding
    		•  1.83109253387887 bayes_pls_golite062009
  • exonuclease activity
    		•  1.68989335095363 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  1.60828797652808 bayes_pls_golite062009
  • RNA polymerase activity
    		•  1.60828797652808 bayes_pls_golite062009
  • damaged DNA binding
    		•  1.08077297289305 bayes_pls_golite062009
  • catalytic activity
    		•  1.04899053677564 bayes_pls_golite062009
  • chromatin binding
    		•  0.953917901573139 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.78558451404229 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.433956339585542 bayes_pls_golite062009
  • protein binding
    		•  0.354190470641287 bayes_pls_golite062009
  • nuclease activity
    		•  0.332024848299731 bayes_pls_golite062009
  • single-stranded DNA specific exodeoxyribonuclease activity
    		•  0.19596408995795 bayes_pls_golite062009
  • 5'-3' exonuclease activity
    		•  0.154583332107704 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle