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Protein Overview: csx2

General Information:
Name(s) found: csx2 / SPBC17G9.08c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • Arf GAP protein [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 870 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed articleLink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: small GTPase mediated signal transduction [ICLink to PubMed article]
    response to arsenic [IMPLink to PubMed article]
    regulation of GTPase activity [ISSLink to PubMed article]
    regulation of ARF GTPase activity [IEA]
    response to cadmium ion [IMPLink to PubMed article]
    intracellular protein transport [RCALink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    ARF GTPase activator activity [IEA]
    GTPase activator activity [ISSLink to PubMed article]
    phospholipid binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGHVDPVHF ERLKIQSVTF GSANDNASLQ VHNVSKSPEY SKYSYSRKNN EPIEFIQLRE  60
   61 EEGPIVKVEE EDGLTLRFQL EFHAQEGKRD VTNLTCVYGT SPQQLDRLIT REFSSDANFQ 120
  121 NNHQVFLIGN IEFHSNENSK KIEWTWSNQS LHTLYFRNGG SPIYLCFAEY DKRLNCLVPL 180
  181 KTFQFYVTES DQDSTPATPF PMPMHLAEET ATSPEISDAP PLSGNVDPLP INSPPLTNPV 240
  241 ARDIDQTEPE DGPLFRATIL NYERTTHDMR MVLKKLIKRI EHVAHSHGLL YMSYKELMSA 300
  301 FERVATINPP AFKPFLDHYY AAAAQSFDSF NIDRARLLRN FLIEPLRKIY DTDIKNVSTK 360
  361 KKDFEETSRD YYTSLSRYLS KSEKETSSDK TKESKFAAKK RDFELSRFDY YSYMQDINGG 420
  421 RKGQEVLSVL TSFAANDYNL IHSSLTDIDA LRPSIIQLQD IVTEANKEFQ LLRAEREERR 480
  481 RYIETSSREL EDKDAEIAAQ AYKAKVDQDT SAKQGLLLAF SKSTSDLQVV GKSGWHKYWV 540
  541 VLDHGKICEY ANWKQSLELH TEPIDLLMAT VRPAQSVSRK FCFEVITPQT KRTYQATSKA 600
  601 EMHSWIEAIQ YSISESIVQK GKGTSMNSEE TSVKHGPTST IGKALQRVAS VTSPSRHNSD 660
  661 SKEKKQTKSP SLVKTLKEMH SSDQSCADCN TTARVEWCAI NFPVVLCIDC SGIHRSLGTH 720
  721 ITKIRSLTLD KFNPETVDLL YATGNSFVNE IYEGGITDWK IKNFENQERR VQFVKDKYLY 780
  781 KRFIKSSFSH DPNTGLLESI EHSNLKEAVL CLALGADVNY QRAVVKALLK NNYLIAELLT 840
  841 LNGASLNVDE VTMETLSARA QAFVMNRATP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..189] PSI-BLAST 16.69897 Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K
    2 View Details [190..234] PSI-BLAST 12.09691 Heavy meromyosin subfragment
    3 View Details [235..612] PSI-BLAST 19.69897 No description for 2elbA was found.
    4 View Details [613..870] PSI-BLAST 15.0 Pyk2-associated protein beta; Pyk2-associated protein beta ARF-GAP domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.65091781683225 bayes_pls_golite062009
  • protein binding
    		•  2.12168271674167 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.66986263418539 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.64990514605397 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.55319485371003 bayes_pls_golite062009
  • signal transducer activity
    		•  1.55319485371003 bayes_pls_golite062009
  • transporter activity
    		•  1.28986800087234 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.2550809703725 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.25381967078645 bayes_pls_golite062009
  • enzyme binding
    		•  1.17212675145623 bayes_pls_golite062009
  • phospholipid binding
    		•  1.09683218092034 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.90578029954417 bayes_pls_golite062009
  • small GTPase binding
    		•  0.8507658747425 bayes_pls_golite062009
  • GTPase binding
    		•  0.82889812790119 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.745321902095093 bayes_pls_golite062009
  • phosphoinositide binding
    		•  0.71817045430443 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.54401901869178 bayes_pls_golite062009
  • receptor binding
    		•  0.50127063593663 bayes_pls_golite062009
  • kinase binding
    		•  0.39940885913863 bayes_pls_golite062009
  • receptor activity
    		•  0.353510125274044 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.207829786337892 bayes_pls_golite062009
  • lipid binding
    		•  0.179561240451969 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase signaling protein activity
    		•  0.13700176999256 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  0.10105990547756 bayes_pls_golite062009
  • protein kinase binding
    		•  0.0918356351234999 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle