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Protein Overview: cdc37

General Information:
Name(s) found: cdc37 / SPBC9B6.10 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • Hsp90 co-chaperone Cdc37 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 466 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: protein folding [IGILink to PubMed article]
    regulation of mitotic cell cycle [IMPLink to PubMed article]
    positive regulation of stress-activated protein kinase signaling pathway [TASLink to PubMed article]
    Molecular Function: heat shock protein binding [IPILink to PubMed article]
    protein binding [IPILink to PubMed articleLink to PubMed article]
    protein homodimerization activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIDYSKWDK LELSDDSDIE VHPNVDKKSF IRWRQRDIHE KRAVRKQKME DIKGAMAMNR  60
   61 RLLSRISEME TVLEKESPSD PYVLLGSFLE AKKSEDMDSA IPGGMSYHHM LMSLLKVIKD 120
  121 AEDTTEEKSM DDSDKCLRRL KSHKERLLKL LEDAQKEYDT LEAESKNYIT SEDLHLGFDS 180
  181 TYVQKKEPEK PKKTKTKKET IQVIESLNNP TPPTDFPGAK EQASTGNAPK NPVNENESED 240
  241 EEGLSLSEDG KKFANIDFGD YSSSEEFLKE HLNILADEEE SDAILLEAFN AELEGKPSLA 300
  301 KQYVHQALLI SYCRQLGPNG LSIFFQKIKD PNHQSQRLFL EDVHNTYVRI HERSAAISKE 360
  361 QAESGEGVEQ IQLCAVDPNT KLSITIPEAG STDPETQKAR AAFESFPPNL QKALMTNDLD 420
  421 KINVVLGKMA VENAEEVVEK LSSTGMLSIE EGIIDTTKGE TIPQLS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..281] PSI-BLAST 3.221849 Heavy meromyosin subfragment
    2 View Details [282..466] PSI-BLAST 56.69897 Complex of Hsp90 and P50

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • unfolded protein binding
    		•  2.81356017403888 bayes_pls_golite062009
  • binding
    		•  2.27048396817643 bayes_pls_golite062009
  • protein binding
    		•  2.017826082168 bayes_pls_golite062009
  • chaperone binding
    		•  1.0201051634973 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  0.88466785845109 bayes_pls_golite062009
  • kinase regulator activity
    		•  0.73391412820573 bayes_pls_golite062009
  • heat shock protein binding
    		•  0.37877224532954 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle