YRC Public Data Repository - Protein Structure Prediction

Protein:	cdc37
Organism:	Schizosaccharomyces pombe
Length:	466 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cdc37.

Description	E-value	Query Range	Subject Range
gi\|42553187, gi\|... - gi\|46124703\|ref\|XP_386905.1\| hypothetical protein FG06729.1 [Gibberella zeae PH-1], gi\|42553187\|gb\|E...	442.0	[0..1]	[465..880]
gi\|38105928, gi\|... - gi\|39940500\|ref\|XP_359787.1\| hypothetical protein MG04990.4 [Magnaporthe grisea 70-15], gb\|EAA52298....	426.0	[0..1]	[465..89]
gi\|32403890, gi\|... - gi\|32403890\|ref\|XP_322558.1\| hypothetical protein [Neurospora crassa], gi\|28917868\|gb\|EAA27555.1\| hy... gi\|85081799 - gi\|85081799\|ref\|XP_956791.1\| hypothetical protein NCU00472 [Neurospora crassa OR74A]	395.0	[0..1]	[464..1]
gi\|40745727, gi\|... - gi\|67523189\|ref\|XP_659655.1\| hypothetical protein AN2051.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	381.0	[0..1]	[465..1]
gi\|159125257 - gi\|159125257\|gb\|EDP50374.1\| Hsp90 co-chaperone Cdc37 [Aspergillus fumigatus A1163] gi\|66849459, gi\|... - gi\|70993956\|ref\|XP_751825.1\| Hsp90 co-chaperone Cdc37 [Aspergillus fumigatus Af293], gi\|66849459\|gb\|...	378.0	[0..1]	[465..1]
gi\|88183763, gi\|... - gi\|88183763\|gb\|EAQ91231.1\| hypothetical protein CHGG_03166 [Chaetomium globosum CBS 148.51], gi\|1162...	369.0	[0..1]	[464..1]
gi\|169771673 - gi\|169771673\|ref\|XP_001820306.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83768165 - gi\|83768165\|dbj\|BAE58304.1\| unnamed protein product [Aspergillus oryzae]	363.0	[0..1]	[465..1]
gi\|49078720, gi\|... - gi\|71022775\|ref\|XP_761617.1\| hypothetical protein UM05470.1 [Ustilago maydis 521], ref\|XP_403085.1\| ...	361.0	[0..1]	[459..1]
gi\|114197688, gi... - gi\|115492401\|ref\|XP_001210828.1\| hypothetical protein ATEG_00742 [Aspergillus terreus NIH2624], gi\|1...	359.0	[0..1]	[465..1]
gi\|50058981 - gi\|50058981\|gb\|AAT69235.1\| CDC37 [Exophiala dermatitidis]	353.0	[0..1]	[462..1]

Back

Predicted Domain #1

Region A:
Residues: [1-281]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIDYSKWDK LELSDDSDIE VHPNVDKKSF IRWRQRDIHE KRAVRKQKME DIKGAMAMNR  60
   61 RLLSRISEME TVLEKESPSD PYVLLGSFLE AKKSEDMDSA IPGGMSYHHM LMSLLKVIKD 120
  121 AEDTTEEKSM DDSDKCLRRL KSHKERLLKL LEDAQKEYDT LEAESKNYIT SEDLHLGFDS 180
  181 TYVQKKEPEK PKKTKTKKET IQVIESLNNP TPPTDFPGAK EQASTGNAPK NPVNENESED 240
  241 EEGLSLSEDG KKFANIDFGD YSSSEEFLKE HLNILADEEE S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.221849
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [282-466]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAILLEAFNA ELEGKPSLAK QYVHQALLIS YCRQLGPNGL SIFFQKIKDP NHQSQRLFLE  60
   61 DVHNTYVRIH ERSAAISKEQ AESGEGVEQI QLCAVDPNTK LSITIPEAGS TDPETQKARA 120
  121 AFESFPPNLQ KALMTNDLDK INVVLGKMAV ENAEEVVEKL SSTGMLSIEE GIIDTTKGET 180
  181 IPQLS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.69897
Match:	1us7B
Description:	Complex of Hsp90 and P50
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
unfolded protein binding	2.81356017403888	bayes_pls_golite062009
binding	2.27048396817643	bayes_pls_golite062009
protein binding	2.017826082168	bayes_pls_golite062009
chaperone binding	1.0201051634973	bayes_pls_golite062009
protein kinase regulator activity	0.88466785845109	bayes_pls_golite062009
kinase regulator activity	0.73391412820573	bayes_pls_golite062009
heat shock protein binding	0.37877224532954	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: