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Protein Overview: DIP1-PD

General Information:
Name(s) found: DIP1-PD / FBpp0077065 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • The gene DISCO Interacting Protein 1 is referred to in FlyBase by the symbol Dmel\DIP1 (CG17686, FBgn0024807). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:21495823..21501185. It has the cytological map location 20A4-20A5. There is experimental evidence that it has the molecular function</span>: double-stranded RNA binding; protein binding. The biological processes in which it is involved are not known. 18 alleles are reported. The phenotypes of these alleles are annotated with: eye; antenna; wing margin bristle; head capsule; haltere; wing; arista; capitellum; wing vein. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 410 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    chromatin [NAS]
    Biological Process: NONE FOUND
    Molecular Function: protein binding [IPI]
    double-stranded RNA binding [IDA][ISS][NAS]
    chromatin binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRNRRAFAG NNKPFVFGGI YNPNATVKPL IQMPLQAANV QEQQSSPVAL YPTSASPVAV  60
   61 QSPQDAFLAV QSPGAPAPVQ LANSSDQQNN PDADAIASKL PMPVIIKEEP ISVNDEPSVD 120
  121 NIEDNTSAST SASGIGGKIP FKKIFQKRKK SSERTRDKKL RQNRQLRKSM LPKNALMALN 180
  181 EVKGVTISDF TIDSNTDGGF TAVVTVNSNQ YEGKGTSKMT AKNAACEKAW RDFIIAKMTP 240
  241 KPPRIHQVEM GSEPMDINED EADAPDDDLP MLNLASFAIY KLFAEWEREG YVVPEMHPSA 300
  301 NAAQQAGGDA GTPVPPVPKE PKKPPVRTEL PSGWETMHPA TILCIMRPGL NYVDYGSSGD 360
  361 KTNGMQHLGI MVDNQEFHAN GRSKKIARRN VAVKVCNSLF GTNFTYSDTT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..156] MSA 3.094995 View MSA. No confident structure predictions are available.
    2 View Details [157..243] PSI-BLAST 6.09691 Solution structure of the N-terminal dsRBD from hypothetical protein BAB28848
    3 View Details [244..319] deduced N/A No confident structure predictions are available.
    4 View Details [320..410] PSI-BLAST 16.522879 Crystal structure of RNase III Mutant E110K from Aquifex Aeolicus complexed with ds-RNA at 2.15 Angstrom Resolution

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.94193673826237 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.04630961873875 bayes_pls_golite062009
  • RNA binding
    		•  0.41703783699663 bayes_pls_golite062009
  • protein binding
    		•  0.32114973384806 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  1.94193673826237 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.04630961873875 bayes_pls_golite062009
  • RNA binding
    		•  0.41703783699663 bayes_pls_golite062009
  • protein binding
    		•  0.32114973384806 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle