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View Structure Prediction Details

Protein: DIP1-PD
Organism: Drosophila melanogaster
Length: 410 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIP1-PD.

Description E-value Query
Range
Subject
Range
gi|7677268 - gi|7677268|gb|AAF67101.1| Ultrabithorax binding protein 1 [Drosophila melanogaster]
310.0 [0..1] [410..1]

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Predicted Domain #1
Region A:
Residues: [1-156]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRNRRAFAG NNKPFVFGGI YNPNATVKPL IQMPLQAANV QEQQSSPVAL YPTSASPVAV  60
   61 QSPQDAFLAV QSPGAPAPVQ LANSSDQQNN PDADAIASKL PMPVIIKEEP ISVNDEPSVD 120
  121 NIEDNTSAST SASGIGGKIP FKKIFQKRKK SSERTR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [157-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKKLRQNRQL RKSMLPKNAL MALNEVKGVT ISDFTIDSNT DGGFTAVVTV NSNQYEGKGT  60
   61 SKMTAKNAAC EKAWRDFIIA KMTPKPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.09691
Match: 1whqA
Description: Solution structure of the N-terminal dsRBD from hypothetical protein BAB28848
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.94193673826237 bayes_pls_golite062009
nucleic acid binding 1.04630961873875 bayes_pls_golite062009
RNA binding 0.41703783699663 bayes_pls_golite062009
protein binding 0.32114973384806 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [244-319]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RIHQVEMGSE PMDINEDEAD APDDDLPMLN LASFAIYKLF AEWEREGYVV PEMHPSANAA  60
   61 QQAGGDAGTP VPPVPK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [320-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPKKPPVRTE LPSGWETMHP ATILCIMRPG LNYVDYGSSG DKTNGMQHLG IMVDNQEFHA  60
   61 NGRSKKIARR NVAVKVCNSL FGTNFTYSDT T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.522879
Match: 1rc7A
Description: Crystal structure of RNase III Mutant E110K from Aquifex Aeolicus complexed with ds-RNA at 2.15 Angstrom Resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.94193673826237 bayes_pls_golite062009
nucleic acid binding 1.04630961873875 bayes_pls_golite062009
RNA binding 0.41703783699663 bayes_pls_golite062009
protein binding 0.32114973384806 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle