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Protein Overview: Syx16-PA

General Information:
Name(s) found: Syx16-PA / FBpp0077022 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Syntaxin 16 is referred to in FlyBase by the symbol Dmel\Syx16 (CG1467, FBgn0031106). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:20263361..20264807. It has the cytological map location 19C6. Based on sequence similarity, it is predicted to have molecular function</span>: SNAP receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: synaptic vesicle docking during exocytosis. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 352 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IDA]
    Golgi apparatus [IDA]
    Golgi membrane [IC]
    plasma membrane [ISS][NAS]
    lysosome [IDA]
    Biological Process: synaptic vesicle docking during exocytosis [ISS]
    vesicle-mediated transport [IEA][NAS]
    intracellular protein transport [IEA]
    neurotransmitter secretion [NAS]
    Molecular Function: SNAP receptor activity [IEA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSRNLTEVF VIMRNNASKN RNHYDDRRGS DAERLLKHSV REAEEGLELQ DDYGTPPAWL  60
   61 DKFEEAQYTM SKIKPKLDEL GSLHARHLLR PAFDDQRDDE CDIEVLSQIV SKLITSTHRH 120
  121 IQCVRSSIGV GSKMEQCLTV NAVHCALLQL QELTVKFRAS QNAYLLQLNS REERSQKYFD 180
  181 DGGGAGAGDV FTNVELGEQS AENFVDSFDN FLQPPAEGKS GNGYLFEDDE QAIDDHFQRP 240
  241 PASRMTQQQL LLFEEENTRV AQHREQEVTK IVKSIYDLND IFKDLGHMVQ EQGTVLDRID 300
  301 YNVEQTQTRV SEGLRQLHKA EMYQRKNRKM CVILVLAAVT FFMLLLLILT KL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..352] PSI-BLAST 22.154902 Syntaxin 1A N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • calcium channel inhibitor activity
    		•  3.742507334159 bayes_pls_golite062009
  • SNAP receptor activity
    		•  3.50393203740159 bayes_pls_golite062009
  • protein transporter activity
    		•  2.96543140800925 bayes_pls_golite062009
  • binding
    		•  2.13344290488739 bayes_pls_golite062009
  • myosin head/neck binding
    		•  1.76421579737303 bayes_pls_golite062009
  • transporter activity
    		•  1.74189664015129 bayes_pls_golite062009
  • phosphatidic acid binding
    		•  1.58155184524859 bayes_pls_golite062009
  • protein binding
    		•  1.51700626946713 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.49085442233849 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.13101548288086 bayes_pls_golite062009
  • excitatory extracellular ligand-gated ion channel activity
    		•  0.86350507004267 bayes_pls_golite062009
  • extracellular ligand-gated ion channel activity
    		•  0.86350507004267 bayes_pls_golite062009
  • SNARE binding
    		•  0.71459772253941 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.643064875848901 bayes_pls_golite062009
  • gated channel activity
    		•  0.621670335227137 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  0.41937155561589 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  0.41937155561589 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.370484918396857 bayes_pls_golite062009
  • channel activity
    		•  0.0647076360772156 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.0647076360772156 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.0435980899803177 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0172309833091902 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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