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Protein Overview: FBpp0310189, os-...

General Information:
Name(s) found: FBpp0310189 [FlyBase]
os-PB / FBpp0111760 [FlyBase]
os-PA / FBpp0074353 [FlyBase]
Description(s) found:
Found 37 descriptions.
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  • type=protein; loc=X:complement(18200127..18200861,18201051..18201200,18201276..18201632); ID=FBpp0310189; name=os-PC; parent=FBgn0004956,FBtr0343592; dbxref=FlyBase:FBpp0310189,FlyBase_Annotation_IDs:CG5993-PC; MD5=85b5cbe7cdceef741997d2ab99353cca; length=413; release=r5.56; species=Dmel; [FlyBase]
  • The gene outstretched is referred to in FlyBase by the symbol Dmel\os (CG5993, FBgn0004956). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18199377..18203021. It has the cytological map location 17A5. It is reported to have molecular function</span>: morphogen activity; receptor binding; cytokine activity. There is experimental evidence that it is involved in the biological process</span>: hindgut morphogenesis; border follicle cell migration; foregut morphogenesis; eye-antennal disc morphogenesis; ovarian follicle cell development; primary sex determination; stem cell division; positive regulation of JAK-STAT cascade. 37 alleles are reported. The phenotypes of these alleles are annotated with 38 unique terms, many of which group under: organ system; female germline cyst; anatomical structure; embryonic segment; thoracic segment; adult segment; embryonic abdomen; imaginal precursor; external compound sense organ; abdominal segment 8; peripheral nervous system. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene outstretched is referred to in FlyBase by the symbol Dmel\os (CG5993, FBgn0004956). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18199377..18203021. It has the cytological map location 17A5. It is reported to have molecular function</span>: morphogen activity; receptor binding; cytokine activity. There is experimental evidence that it is involved in the biological process</span>: hindgut morphogenesis; border follicle cell migration; foregut morphogenesis; eye-antennal disc morphogenesis; ovarian follicle cell development; primary sex determination; stem cell division; positive regulation of JAK-STAT cascade. 37 alleles are reported. The phenotypes of these alleles are annotated with 38 unique terms, many of which group under: organ system; female germline cyst; anatomical structure; embryonic segment; thoracic segment; adult segment; embryonic abdomen; imaginal precursor; external compound sense organ; abdominal segment 8; peripheral nervous system. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 413 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [NAS][TAS]
    proteinaceous extracellular matrix [TAS]
    Biological Process: foregut morphogenesis [IMP]
    blastoderm segmentation [TAS]
    germ-line stem cell division [TAS]
    eye-antennal disc morphogenesis [IMP]
    sex determination, establishment of X:A ratio [NAS]
    border follicle cell migration [IMP][TAS]
    sex determination [NAS]
    hindgut morphogenesis [IMP]
    defense response [NAS]
    JAK-STAT cascade [NAS][TAS]
    positive regulation of JAK-STAT cascade [IDA]
    primary sex determination [IMP][NAS]
    embryonic development via the syncytial blastoderm [TAS]
    somatic stem cell division [TAS]
    ovarian follicle cell development [IMP]
    stem cell division [IMP][TAS]
    Molecular Function: cytokine activity [TAS]
    receptor binding [NAS][TAS]
    morphogen activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARPLLLLLP ILLVLLLAAQ LPHLAEGRST TSSGGLTVID SERLRIRTTS STASAQHPNQ  60
   61 GTIPASAASP RKRHRKRNSN WIDYRNFDEN TTALEWANPC GGNYHPSAGD RFNRQRPRQS 120
  121 FNQLKRHAFR EYRSLNSSQD SAIDIRNMTM WSLHTHNYKF LPKLKPNSTI ALKRWYRNMQ 180
  181 TYVASFAYLR RQQIRWDQRS ITRESSTARE LRELLLSSRR ILCELETAVN QTQSPRQKQR 240
  241 RSGAAVTAVG GTTMLGQQLP QISRLEMNKR LKLRSKTSGP GMGGAASSAS MAAGEADSID 300
  301 MRFVKHHYYD FLRTMYQLLR RDGKRVRSRP RKHHKKQQRS QKKLLQQQQQ LADQLEQRWR 360
  361 SSTLNGKEFN EVSKPVAGGA AGVADVAGVS GGGSNQFARG RRGKRQSKRV QRT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..168] MSA 1.00697 View MSA. No confident structure predictions are available.
    2 View Details [169..413] MSA 1.006951 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle