Protein Overview: FBpp0294044, Pp2...

General Information:
Name(s) found:	FBpp0301546 [FlyBase] FBpp0294044 [FlyBase] Pp2B-14D-PA / FBpp0074069 [FlyBase]
Description(s) found: Found 36 descriptions. SHOW ALL	type=protein; loc=X:complement(16451728..16453440); ID=FBpp0301546; name=Pp2B-14D-PC; parent=FBgn0011826,FBtr0309793; dbxref=FlyBase:FBpp0301546,FlyBase_Annotation_IDs:CG9842-PC,REFSEQ:NP_001245715,GB_protein:AFH07428; MD5=2a6b9e8a0ca9a1c81e96417aa2f2635e; length=570; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=X:complement(16451728..16453440); ID=FBpp0294044; name=Pp2B-14D-PB; parent=FBgn0011826,FBtr0305593; dbxref=REFSEQ:NP_001245716,GB_protein:AFH07429,FlyBase:FBpp0294044,FlyBase_Annotation_IDs:CG9842-PB; MD5=2a6b9e8a0ca9a1c81e96417aa2f2635e; length=570; release=r5.56; species=Dmel; [FlyBase] The gene Protein phosphatase 2B at 14D is referred to in FlyBase by the symbol Dmel\Pp2B-14D (CG9842, FBgn0011826). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16450797..16454052. It has the cytological map location 14E1-14E3. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: female meiosis; wing disc development. 11 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor cell R7; eye; interommatidial bristle; eye photoreceptor cell; wing; ommatidium; photoreceptor cell R4; wing vein; photoreceptor cell R3. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	570 amino acids
Gene Ontology:
Cellular Component:	calcineurin complex [ISS][NAS]
Biological Process:	wing disc development [IMP] female meiosis [IMP] protein amino acid dephosphorylation [ISS][NAS]
Molecular Function:	protein serine/threonine phosphatase activity [ISS][NAS] calmodulin binding [TAS] calcium-dependent protein serine/threonine phosphatase activity [ISS] protein binding [IPI] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSNNQSSSV AQAATSARTV SAGSAEATDA NSTASNNNNN SSSTAAAGNN SDNSSPTTGT  60
   61 GTGASTGKLH GGHTAVNTKE RVVDSVPFPP SHKLTLAEVF DQRTGKPNHE LLKQHFILEG 120
  121 RIEEAPALKI IQDGAALLRQ EKTMIDIEAP VTVCGDIHGQ FYDLMKLFEV GGSPASTKYL 180
  181 FLGDYVDRGY FSIECVLYLW SLKITYPQTL FLLRGNHECR HLTEYFTFKQ ECKIKYSERV 240
  241 YDACMDAFDC LPLAALMNQQ FLCVHGGLSP EIHELEDIRR LDRFKEPPAF GPMCDLLWSD 300
  301 PLEDFGNEKN SDFYTHNSVR GCSYFYSYAA CCDFLQNNNL LSIIRAHEAQ DAGYRMYRKS 360
  361 QTTGFPSLIT IFSAPNYLDV YNNKAAVLKY ENNVMNIRQF NCSPHPYWLP NFMDVFTWSL 420
  421 PFVGEKVTEM LVNVLNICSD DELMTEESEE PLSDDEAALR KEVIRNKIRA IGKMARVFSV 480
  481 LREESESVLQ LKGLTPTGAL PLGALSGGKQ SLKNAMQGFS PNHKITSFAE AKGLDAVNER 540
  541 MPPRRDQPPT PSEDPNQHSQ QGGKNGAGHG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
phosphoprotein phosphatase activity	11.6417995308386	bayes_pls_golite062009
protein serine/threonine phosphatase activity	10.6440947462013	bayes_pls_golite062009
phosphatase activity	10.5525832502704	bayes_pls_golite062009
phosphoric ester hydrolase activity	10.3702645338723	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	9.02791306892273	bayes_pls_golite062009
calcium-dependent protein serine/threonine phosphatase activity	7.59009048424811	bayes_pls_golite062009
myosin phosphatase activity	5.31703100176823	bayes_pls_golite062009
hydrolase activity	3.13006743434485	bayes_pls_golite062009
structural constituent of muscle	2.91086263632625	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.68552051869632	bayes_pls_golite062009
kinase activity	1.67788383575784	bayes_pls_golite062009
structural molecule activity	1.5850868178597	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.57807175808088	bayes_pls_golite062009
protein kinase activity	1.4514460578232	bayes_pls_golite062009
binding	1.44538582463569	bayes_pls_golite062009
catalytic activity	1.39852585255405	bayes_pls_golite062009
transferase activity	1.3407391509244	bayes_pls_golite062009
protein binding	1.33435965029646	bayes_pls_golite062009
transporter activity	1.24767072239634	bayes_pls_golite062009
signal transducer activity	1.08090214431427	bayes_pls_golite062009
molecular transducer activity	1.08090214431427	bayes_pls_golite062009
calmodulin binding	0.77173071932406	bayes_pls_golite062009
protein serine/threonine kinase activity	0.66803085638835	bayes_pls_golite062009
substrate-specific transporter activity	0.528189469950839	bayes_pls_golite062009
protein transporter activity	0.10469955758282	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..102]	PSI-BLAST	85.39794	PP5 structure
2	View Details	[103..570]	PSI-BLAST	170.0	Protein phosphatase-2B (PP-2B, calcineurin A subunit)

Protein Overview: FBpp0294044, Pp2...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: