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Protein Overview: caz-PB

General Information:
Name(s) found: caz-PB / FBpp0073996 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene cabeza is referred to in FlyBase by the symbol Dmel\caz (CG3606, FBgn0011571). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:16182879..16187553. It has the cytological map location 14B8-14B9. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity; mRNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription initiation from RNA polymerase II promoter. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 399 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    transcription factor TFIID complex [ISS]
    catalytic step 2 spliceosome [IDA]
    Biological Process: transcription initiation from RNA polymerase II promoter [ISS]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: nucleic acid binding [IEA]
    zinc ion binding [IEA]
    general RNA polymerase II transcription factor activity [ISS]
    mRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERGGYGGGS GQGYNNFAVP PPNYQQMPNK TGNYNEPPPN YGKQGGGYDS GSGHRGSGGS  60
   61 GNGGGGGGSW NDRGGNSYGN GGASKDSYNK GHGGYSGGGG GGGGGGGGGS GGNDMITQED 120
  121 TIFVSGMDPS TTEQDIETHF GAIGIIKKDK RTMKPKIWLY KNKETGASKG EATVTYDDTN 180
  181 AAQSAIEWFD GRDFNGNAIK VSLAQRQNNW NKGGGGGGGG GGRGGFGGRR GGGGGGGGGG 240
  241 GGGGRFDRGG GGGGGRYDRG GGGGGGGGGG NVQPRDGDWK CNSCNNTNFA WRNECNRCKT 300
  301 PKGDDEGSSG GGGGGGYGGG GGGGGYDRGN DRGSGGGGYH NRDRGGNSQG GGGGGGGGGG 360
  361 YSRFNDNNGG GRGGRGGGGG NRRDGGPMRN DGGMRSRPY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..212] PSI-BLAST 38.69897 Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
    2 View Details [213..302] FFAS03 1.64 Crystal structure of the C-terminal domain of BclA, the major antigen of the exosporium of the Bacillus anthracis spore.
    3 View Details [303..399] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.950788308762215 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.29562225149076 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle