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Protein Overview: CG8239-PA, FBpp0...

General Information:
Name(s) found: FBpp0312007 [FlyBase]
CG8239-PA / FBpp0073903 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • type=protein; loc=X:join(15643285..15643336,15643398..15643468,15643865..15643982,15644043..15644968); ID=FBpp0312007; name=CG8239-PB; parent=FBgn0030683,FBtr0346188; dbxref=FlyBase:FBpp0312007,FlyBase_Annotation_IDs:CG8239-PB; MD5=2a1e752d67b5de34dd9b1435a9329dc2; length=388; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8239 (CG8239, FBgn0030683). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15643210..15645255. It has the cytological map location 13E14. Based on sequence similarity, it is predicted to have molecular function</span>: diphosphomevalonate decarboxylase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: isoprenoid biosynthetic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 388 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: phosphorylation [IEA]
    isoprenoid biosynthetic process [ISS]
    Molecular Function: ATP binding [IEA]
    diphosphomevalonate decarboxylase activity [ISS]
    kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSVTCVAPV NIALIKYWGK RHEELILPVN DSISMTLSTD ELCAKTTVTA SESFETNRMW  60
   61 LNGEEVPFEE SSRLQRCLNE VHRLAVASGS QKVPPTWKLH IASVNNFPTA AGLASSAAGY 120
  121 ACLVYSLSRL YDIPLNEELT TVARQGSGSA CRSLYGGFVQ WHRGALDDGS DSVARQIAPS 180
  181 DHWPNMHVLI LVVNDARKKT ASTRGMQQAV KTSQLIKHRV DQVVPDRIIR LREAIASHDF 240
  241 QAFAEITMKD SNQFHAIALD TYPPCVYMND VSHSIVSFVH DYNERMGSYH AAYTFDAGPN 300
  301 ACLYVLAEHV PHLLSAIQKV FPNDLADGGT YLRGLPIPKV QDAESSKLDS LDVHAKNAFR 360
  361 YIIHTKVGEG PKELSADNSL LINGLPLK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..388] PSI-BLAST 70.0 Mevalonate 5-diphosphate decarboxylase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • diphosphomevalonate decarboxylase activity
    		•  2.34245588421319 bayes_pls_golite062009
  • binding
    		•  1.48300512137561 bayes_pls_golite062009
  • catalytic activity
    		•  0.836142537655721 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.66774567862554 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.49664490095304 bayes_pls_golite062009
  • structural molecule activity
    		•  0.40691892506083 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.369771518688522 bayes_pls_golite062009
  • protein binding
    		•  0.214066724623027 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.212099606954236 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle