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Protein Overview: mus101-PA

General Information:
Name(s) found: mus101-PA / FBpp0073648 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene mutagen-sensitive 101 is referred to in FlyBase by the symbol Dmel\mus101 (CG11156, FBgn0002878). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:13616322..13621145. It has the cytological map location 12B4. Its molecular function is unknown. It is reported to be involved in the biological process</span>: mitosis; oogenesis. 12 alleles are reported. The phenotypes of these alleles are annotated with: heterochromatin; imaginal disc; chromatin. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1425 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: oogenesis [TAS]
    mitosis [TAS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSISMSMDET ICAYFVNNLK PGDGGVQEAD TLQQFEAARE LLGQQLAETQ IRQIKPSEGY  60
   61 PLIAAGNLTK KDVFVLTQFE GEFFEQLQQT RALILGPPCL ITCLRRNEPI PEGSSAIYST 120
  121 AMRDLQVSAT GITPQKKEEL SRLINWMGGI YFQSFGHRTT HLISNTIKSS KYEQATLNGV 180
  181 PVMHVDWVQY VWDQSRRSQR EGIMATDPDF DKYRLPIFFG ANITCSGLDV ARKDQVMRLV 240
  241 NDNGGIYHRA FRSQVVDIVI TEQTKTDTEK YKAAIRYKKD VLLPEWIFDS CNRGYALPTK 300
  301 DYEVRPGKTS STPTKTTRPG AAPGADQTHL SDLSRISFVS GSRRMCSDLS TVNESVSSVG 360
  361 SSSPAKQLLK QATSSGRNYQ QVLAEIEPRQ AKKAGAFLDG CCVYLSGFRS EEREKLNRVL 420
  421 NTGGATRYDE ANEGISHIIV GQLDDAEYRQ WQRDGLMGSV HVVRLDWLLE SIRAGRVVSE 480
  481 LVHRVSMPQN REPDVASPAS KRTLRSMNHS FKQPTLPIKK KLFDQEPDPV QEQEHEEPDH 540
  541 TLLDQYSQDQ GAVAQLPPAD VSLLQPAASS TQMDIRQRVS VANPKPPAEG LQLPDLSAST 600
  601 LSIDFDKLDY FAGVSVYVHR ECFNEEFFNQ MLTECEAAQG LLVPSSFSDE VDFAIVSFEV 660
  661 AFDVKQLPVK ARHVVTELFL ESCMKKNQLL PIEYYHKHVP ATALRQPLKG MTIVVSIYAG 720
  721 LERDFINATA ELLGASVNKT FIKKEKPLLV CPSAEGSKYE GAIKWNYPVV TSDWLVQCAR 780
  781 TGQKLPFVGY LVGKSPEDFP ISPRLRDSNS RTARRPNEST LVAQPDVTME EAENQPAGSV 840
  841 TPVTAGSPGA PELTPLRNKR VSELAGIPGG SALHRGSNST SSPDSPCTPL SQVGAQQYNL 900
  901 DFLEQFVQRL DTEEGKDCVR EIIREMRENQ TPELERIRRQ ACTPVSRKHQ RPAPGIPDFC 960
  961 LTPEFQQRMA DDFERRWRLP TMKIKPDTPL AVIRQRVMRI TCETLGIEYE ESNAKTPTLS1020
 1021 ESPSTVKKKP PTRTTQATKL NFDRSPKTPK LSLGKKTPLR VSMGSPRSGT QSPFVPNTQS1080
 1081 PIEAAPPRRS DGPTLSEEGQ STINFDKISF EESAVPVLAP DVPTVAPDVK QITDYLKNCE1140
 1141 SRRNSLKRSH DNDMDCGESE VQYVQPFESE GFALGTEDMV DWRDPAEFNA AKRRSSGGSP1200
 1201 KMQYAGIPCF SISCGDDDEK RAELIARITQ LGGKVCENLV NYDDSCTHLL CERPNRGEKM1260
 1261 LACIAAGKWI LNIQYIEQSH ARGDFLDETL YEWGNPKAIN LPTLAPEEEP IAAAVHRWRT1320
 1321 ELSACGGGAF SDHRVILSMN ERSGAPIRNV LRAGGACILE PTTPFSKDPV AKSASHCFVD1380
 1381 VKKAPLSTQD MEYLHKCGVQ VLSQIAINAY LMNGRDADLG KYQLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] PSI-BLAST 6.522879 No description for 2owoA was found.
    2 View Details [203..314] PSI-BLAST 15.69897 Solution structure of the BRCT-c domain from human BRCA1
    3 View Details [315..483] PSI-BLAST 21.0 The third BRCA1 C-terminus (BRCT) domain of Similar to S.pombe rad4+/cut5+ product
    4 View Details [484..610] deduced N/A No confident structure predictions are available.
    5 View Details [611..709] PSI-BLAST 8.154902 DNA-repair protein XRCC1
    6 View Details [710..875] FFAS03 4.14 No description for 2d8mA was found.
    7 View Details [876..1112] deduced N/A No confident structure predictions are available.
    8 View Details [1113..1205] deduced N/A No confident structure predictions are available.
    9 View Details [1206..1425] PSI-BLAST 42.154902 Breast cancer associated protein, BRCA1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.911539062312394 bayes_pls_golite062009
  • protein binding
    		•  0.740170908668509 bayes_pls_golite062009
  • catalytic activity
    		•  0.00504703671568302 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  0.911539062312394 bayes_pls_golite062009
  • protein binding
    		•  0.740170908668509 bayes_pls_golite062009
  • catalytic activity
    		•  0.00504703671568302 bayes_pls_golite062009
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  0.911539062312394 bayes_pls_golite062009
  • protein binding
    		•  0.740170908668509 bayes_pls_golite062009
  • catalytic activity
    		•  0.00504703671568302 bayes_pls_golite062009
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle