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Protein Overview: Ir11a-PA

General Information:
Name(s) found: Ir11a-PA / FBpp0073506 [FlyBase]
Description(s) found:
Found 13 descriptions.
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  • The gene Ionotropic receptor 11a is referred to in FlyBase by the symbol Dmel\Ir11a (CG15732, FBgn0030385). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:12269629..12271788. It has the cytological map location 11A9. Based on sequence similarity, it is predicted to have molecular function</span>: extracellular-glutamate-gated ion channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transport. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 659 amino acids

    Gene Ontology:
    Cellular Component: outer membrane-bounded periplasmic space [IEA]
    Biological Process: transport [IEA]
    Molecular Function: extracellular-glutamate-gated ion channel activity [ISS]
    transporter activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRAESCRD IHNGHSVMRF AILWLFSGCL LPGIQVGIWV VVRAQPTGRD VLLSRLGNQQ  60
   61 NELNTRRLAN ASSYLTRNYI ANRINTLVVR EICVECPYEL SERQRQLVDQ ILASLAPELS 120
  121 VLLHKGTAEE TTWEYTLFVV NDHTAFTGQV FIFPDELLER EFFCIVVVSE IQSRQFVRQT 180
  181 VGSIVKSNLQ MHFVNVVVVA QLEDGTVGTY SYKLFKANCT PGITVRQINH FDRITGKPQQ 240
  241 SMPDLYPVRN GHLGDCPFNV GAAHMPPHLI YKRHKDPPPA SNVSIPAEDL AGIDWDLLQL 300
  301 LAKALKFRIQ LYMPQEPSQI FGEGNVSGCF RQLADGTVSI AIGGLSGSDK RRSLFSKSTV 360
  361 YHQSNFVMVV RRDRYLGRLG PLILPFRGKL WGVIIVILLL AVLSTCWLRS RLGLSHPIED 420
  421 LLTVIVGNPI PDHRLPGKGF LRYLLASWML LTLVLRCAYQ ARLFDVLRLS RHRPLPKDLS 480
  481 GLIKDNYTMV ANGYHDFYPL ELTCRQPLDF SARFERVQRA APDERLTTIA LISNLAYWNH 540
  541 KHPNISRLTF VRQPIYMYHL VIYFPRRFFL RPAIDRKIKQ LLSAGVMAHI ERRYMQYENK 600
  601 RKVASNDPVL LRRITKSIMN GAYRIHGLVI VLATGMFILE LLAGRSNGRL RRWMEWVHQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..252] deduced N/A No confident structure predictions are available.
    2 View Details [253..659] PSI-BLAST 41.522879 Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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