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Protein Overview: Dlic-PB

General Information:
Name(s) found: Dlic-PB / FBpp0073300 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Dynein light intermediate chain is referred to in FlyBase by the symbol Dmel\Dlic (CG1938, FBgn0030276). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11048434..11057245. It has the cytological map location 10A8. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled; motor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of dendrite morphogenesis; dendrite morphogenesis; mitotic spindle organization; oogenesis; microtubule cytoskeleton organization; axon cargo transport. 10 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 398 amino acids

    Gene Ontology:
    Cellular Component: cytoplasmic dynein complex [IDA][ISS]
    dynein complex [ISS]
    microtubule associated complex [ISS]
    Biological Process: axon cargo transport [IMP]
    oogenesis [IMP]
    mitotic spindle organization [IMP]
    microtubule cytoskeleton organization [IMP]
    microtubule-based movement [ISS]
    regulation of dendrite morphogenesis [IMP]
    dendrite morphogenesis [IDA][IMP]
    Molecular Function: motor activity [ISS]
    ATPase activity, coupled [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRLGVWVLD GDPGHTNLLH YALNETNYAH TLVILTVSMT QPWGWLEQLN HWIKVLGQHI  60
   61 DSLQLDAKEK EAARQRLTTT WQSYCEVGDD LDPGSPVKRT MRNNSIDEDD LLPLTEDALI 120
  121 TNLGLDIVVV VTKTDYMTTL EKEYEYRDEH FDFIQQWIRN FCLRHGTSLF YTSVKEDKNC 180
  181 DVLYKYLTHR IYGLPFRTPA LVVEKDAVLI PAGWDSLKKI SILYENMHGV KAENPYTDII 240
  241 KSPPTRKAVS NREAEVQTED EQAFLARQQE ILKQGDQVRG ESPLRSQGVG SNKSGPRTPG 300
  301 TTGQSSPKKI DPKLTPATPG AEGVLANFFN SLLHKKSGSP GTGGPGGAGN PAGPGRTANG 360
  361 TDAVMTPEKL AVRTDAAAEL DRLSRSVKKE IDMSQSEC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..215] FFAS03 1.03 No description for 2p5sA was found.
    2 View Details [216..278] MSA 2.053994 View MSA. No confident structure predictions are available.
    3 View Details [279..398] PSI-BLAST 4.0 No description for 1y0fB was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle