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Protein Overview: Imp-PB, Imp-PA, ...

General Information:
Name(s) found: Imp-PA / FBpp0073276 [FlyBase]
Imp-PB / FBpp0073275 [FlyBase]
Imp-PC / FBpp0073274 [FlyBase]
Description(s) found:
Found 49 descriptions.
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  • The gene IGF-II mRNA-binding protein is referred to in FlyBase by the symbol Dmel\Imp (CG1691, FBgn0030235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10690030..10716815. It has the cytological map location 9F2-9F4. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: nervous system development; spermatogenesis. 51 alleles are reported. The phenotypes of these alleles are annotated with: chorion; egg; macrochaeta. It has 10 annotated transcripts and 10 annotated polypeptides. [FlyBase]
  • The gene IGF-II mRNA-binding protein is referred to in FlyBase by the symbol Dmel\Imp (CG1691, FBgn0030235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10690030..10716815. It has the cytological map location 9F2-9F4. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: nervous system development; spermatogenesis. 51 alleles are reported. The phenotypes of these alleles are annotated with: chorion; egg; macrochaeta. It has 10 annotated transcripts and 10 annotated polypeptides. [FlyBase]
  • The gene IGF-II mRNA-binding protein is referred to in FlyBase by the symbol Dmel\Imp (CG1691, FBgn0030235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10690030..10716815. It has the cytological map location 9F2-9F4. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: nervous system development; spermatogenesis. 51 alleles are reported. The phenotypes of these alleles are annotated with: chorion; egg; macrochaeta. It has 10 annotated transcripts and 10 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 566 amino acids

    Gene Ontology:
    Cellular Component: catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    Biological Process: synaptic growth at neuromuscular junction [IMP]
    spermatogenesis [IEP]
    nervous system development [IMP]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: mRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSNNNSSRL NNNISNNYYQ QKQSLIRYLD RAAVGLNGVE FEGSKLHAEQ LDKNQRRSQR  60
   61 NQRNPYPGMP GPGRQADFPL RILVQSEMVG AIIGRQGSTI RTITQQSRAR VDVHRKENVG 120
  121 SLEKSITIYG NPENCTNACK RILEVMQQEA ISTNKGEICL KILAHNNLIG RIIGKSGNTI 180
  181 KRIMQDTDTK ITVSSINDIN SFNLERIITV KGLIENMSRA ENQISTKLRQ SYENDLQAMA 240
  241 PQSLMFPGLH PMAMMSTPGN GMVFNTSMPF PSCQSFAMSK TPASVVPPVF PNDLQETTYL 300
  301 YIPNNAVGAI IGTRGSHIRS IMRFSNASLK IAPLDADKPL DQQTERKVTI VGTPEGQWKA 360
  361 QYMIFEKMRE EGFMCGTDDV RLTVELLVAS SQVGRIIGKG GQNVRELQRV TGSVIKLPEH 420
  421 ALAPPSGGDE ETPVHIIGLF YSVQSAQRRI RAMMLSTNPP PITKKQKAAK EQLQQQQQSL 480
  481 AGAASSGSQQ QQPQSPSQQQ ALPPQLHHQP VSSASSSSTP PAHHQQQAST AATSHQLQQQ 540
  541 QPSPPPPGNA TAAAAQQQQQ LASSQQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..242] PSI-BLAST 26.221849 No description for 2annA was found.
    2 View Details [243..456] PSI-BLAST 20.69897 Far upstream binding element, FBP, KH3 and KH4 domains
    3 View Details [457..566] MSA 11.216997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle