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Protein Overview: Atg8a-PA

General Information:
Name(s) found: Atg8a-PA / FBpp0071427 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Autophagy-specific gene 8a is referred to in FlyBase by the symbol Dmel\Atg8a (CG32672, FBgn0052672). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10658911..10662368. It has the cytological map location 9E6-9E7. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: regulation of protein ubiquitination; determination of adult lifespan. 11 alleles are reported. The phenotype of these alleles is annotated with: larval salivary gland. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 121 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: determination of adult lifespan [IMP]
    regulation of protein ubiquitination [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFQYKEEHA FEKRRAEGDK IRRKYPDRVP VIVEKAPKAR IGDLDKKKYL VPSDLTVGQF  60
   61 YFLIRKRIHL RPEDALFFFV NNVIPPTSAT MGSLYQEHHE EDYFLYIAYS DENVYGMAKI 120
  121 N

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..121] PSI-BLAST 52.69897 GABA(A) receptor associated protein GABARAP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • tubulin binding
    		•  3.8719684227967 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  3.71144418714309 bayes_pls_golite062009
  • microtubule binding
    		•  3.61517229466799 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  3.30801071565148 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.11253399564789 bayes_pls_golite062009
  • beta-tubulin binding
    		•  2.878827078106 bayes_pls_golite062009
  • binding
    		•  2.786655943372 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  2.72499875710239 bayes_pls_golite062009
  • GABA receptor binding
    		•  2.41579236188889 bayes_pls_golite062009
  • protein tag
    		•  2.15059229834935 bayes_pls_golite062009
  • protein binding
    		•  1.86841453215444 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.42747465816672 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.32707653701567 bayes_pls_golite062009
  • DNA binding
    		•  1.22622447288034 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.87452559909702 bayes_pls_golite062009
  • signal transducer activity
    		•  0.87452559909702 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.80391127659342 bayes_pls_golite062009
  • hydrolase activity
    		•  0.79940718386175 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.753885975469065 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.599634454232833 bayes_pls_golite062009
  • structural molecule activity
    		•  0.576819726104993 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.536856055841234 bayes_pls_golite062009
  • kinase activity
    		•  0.506057697290914 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.410719674374641 bayes_pls_golite062009
  • protein kinase activity
    		•  0.325253662829604 bayes_pls_golite062009
  • enzyme binding
    		•  0.240262781026149 bayes_pls_golite062009
  • transferase activity
    		•  0.236208643697075 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle