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Protein Overview: CG34408-PA

General Information:
Name(s) found: CG34408-PA / FBpp0071374 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG34408 (CG34408, FBgn0085437). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10114143..10123948. It has the cytological map location 9B4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: GTPase activator activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: regulation of small GTPase mediated signal transduction. 5 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1532 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: regulation of small GTPase mediated signal transduction [IEA]
    Molecular Function: GTPase activator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSEWASLSA QITANSCGAQ CFSVLNKFPA SAGREVVVSV VKQLGTNLGI TQNAEPSHLV  60
   61 KDEEVKWCMD VICFGLSLPL QEHETIKDCV NVYCEWLTAL HPQPRISVPK PICEDANLYA 120
  121 RQIINHFHNL FVPRQGESAD TIKRQAVLCH RVLRTLQQTA QISQLMDRQT WDTLLLFLLA 180
  181 INEILLAPPT VKDDVGDQLC ERVLSVLFEV WLLACVRSFP SPSMWKTLQE SCAMWRHRVA 240
  241 LVDQWNRVNL ALTARLLEFS YGPAFPQLKN ADEDGQLIPI GMSNDCVAQT WYRFLRMIGN 300
  301 PTALCSPHII SKSSHFVQWA LTHEKGAETH QHPCLQQLPQ IFLNAMKGIS SQVDAFLGLS 360
  361 KTSLIGLTGG GARNAISSSS TTTTNAGSTG GTGSGDGSAP APLPTTPTST SGPPSASSSI 420
  421 NSLPLTSMGA GVELAVARPK CNSILHVFHE WLFEAAHIGG DTWRQNRKKQ ACEASKRPSS 480
  481 MIMEHRKGSI SLSQPNSLND PQSLPPTLTI DKYESGRAEA IGTLCKIFCA KKTGEEILPV 540
  541 YLARFYMALQ QCLKITESRE CDETLASILL HSSDLFRLDL DGINVLLPGF IAALEIVLPD 600
  601 KDLKLKTQSM VFNRTELRRS AINILLSIMV LPLHYQTLPI RDLTCESSEK MFTFIQLKSR 660
  661 LMNILMNALQ VETDAQNTHM LLGGLLLCVQ DAVTFEETEL GGGNANLSQN SSGVQHHDAN 720
  721 LLSSACSERS ASLVSAGTAS LGGQTTATMG AGSGSIRDTA SAHDYPSLTI SDDMSFEFGQ 780
  781 ELEGVTTYDN AHALFVRATY LVCHRLISSW KTDLNVSLAA LELLSGLARL HIRETDALEC 840
  841 KRAVKWICDY ICYQCSRPPP AHSKDLHSTI VAAFQCTAAW LMQHPYLLQD KDCLQTVLEV 900
  901 VELGISGTKS QSKGTDIPKF KDEKELKPAS MRVRDAAENL LTIILEQVGY FPSECGPESI 960
  961 SSLLDELALM KHCNSMVPAA AASSEQAIAK FKYFVTENST ILALLEEPLG NDQDPQPTVT1020
 1021 LLIRGPFGRH AWTMQLRHLP RSKSGIKYHA INPGRPIPMN DVTQRLDSEQ KNFPDGVDKV1080
 1081 QPCVADYSIP TIEQMREQYG TAVIRELESL LENQSIHEKL AWAEADTSAD SLSHAQECVP1140
 1141 PTVCHEFHAA RLFLSHFGFL GFETRNPQNP AEALGNPPQR PLIVLDTKSA AFAADLDRLD1200
 1201 KLSARTHDSV YVFYVKSGQT SAQQIIANMG EESSASHDPH FASMLQTLGW PVQVSEHSGW1260
 1261 TGFAHNSWSL KGTPEEQLKS TANELNYNGS QRVLYWADVS SEIAFVVPTT WNLRYNSDTC1320
 1321 DSGSISSTDQ IGSSNVWTRG EADSAAGLAK SKSRNLSLEL DTNRRDVKEP VPPTRRKGNV1380
 1381 TKPTLLAQAP AKIFLVWLES YEDYLNFPLE DLLAYTRTGE ELQTQQLPRA SDCHVIFVHS1440
 1441 LLSGLLRVKL QGPPGRMSFA TPLVDGMVLS RRVVGNLVRQ TALNISRRRR LDNDNYQPPH1500
 1501 VRRRLKVQDI VQKYKMDLSE ADLLAHLFQR AI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] MSA 1.040989 View MSA. No confident structure predictions are available.
    2 View Details [106..188] deduced N/A No confident structure predictions are available.
    3 View Details [189..404] MSA 1.041976 View MSA. No confident structure predictions are available.
    4 View Details [405..478] deduced N/A No confident structure predictions are available.
    5 View Details [479..715] deduced N/A No confident structure predictions are available.
    6 View Details [716..787] deduced N/A No confident structure predictions are available.
    7 View Details [788..1045] deduced N/A No confident structure predictions are available.
    8 View Details [1046..1426] PSI-BLAST 70.045757 Crystal Structure of the Rap1GAP catalytic domain
    9 View Details [1427..1532] FFAS03 2.23 Crystal Structure of the Rap1GAP catalytic domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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