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View Structure Prediction Details

Protein: CG34408-PA
Organism: Drosophila melanogaster
Length: 1532 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG34408-PA.

Description E-value Query
Range
Subject
Range
gi|5901834 - gi|5901834|gb|AAD55425.1|AF181639_1 BcDNA.GH09358 [Drosophila melanogaster]
1762.0 [0..1] [1532..1]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSEWASLSA QITANSCGAQ CFSVLNKFPA SAGREVVVSV VKQLGTNLGI TQNAEPSHLV  60
   61 KDEEVKWCMD VICFGLSLPL QEHETIKDCV NVYCEWLTAL HPQPR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [106-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISVPKPICED ANLYARQIIN HFHNLFVPRQ GESADTIKRQ AVLCHRVLRT LQQTAQISQL  60
   61 MDRQTWDTLL LFLLAINEIL LAP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [189-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTVKDDVGDQ LCERVLSVLF EVWLLACVRS FPSPSMWKTL QESCAMWRHR VALVDQWNRV  60
   61 NLALTARLLE FSYGPAFPQL KNADEDGQLI PIGMSNDCVA QTWYRFLRMI GNPTALCSPH 120
  121 IISKSSHFVQ WALTHEKGAE THQHPCLQQL PQIFLNAMKG ISSQVDAFLG LSKTSLIGLT 180
  181 GGGARNAISS SSTTTTNAGS TGGTGSGDGS APAPLP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [405-478]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTPTSTSGPP SASSSINSLP LTSMGAGVEL AVARPKCNSI LHVFHEWLFE AAHIGGDTWR  60
   61 QNRKKQACEA SKRP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [479-715]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSMIMEHRKG SISLSQPNSL NDPQSLPPTL TIDKYESGRA EAIGTLCKIF CAKKTGEEIL  60
   61 PVYLARFYMA LQQCLKITES RECDETLASI LLHSSDLFRL DLDGINVLLP GFIAALEIVL 120
  121 PDKDLKLKTQ SMVFNRTELR RSAINILLSI MVLPLHYQTL PIRDLTCESS EKMFTFIQLK 180
  181 SRLMNILMNA LQVETDAQNT HMLLGGLLLC VQDAVTFEET ELGGGNANLS QNSSGVQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [716-787]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HHDANLLSSA CSERSASLVS AGTASLGGQT TATMGAGSGS IRDTASAHDY PSLTISDDMS  60
   61 FEFGQELEGV TT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [788-1045]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDNAHALFVR ATYLVCHRLI SSWKTDLNVS LAALELLSGL ARLHIRETDA LECKRAVKWI  60
   61 CDYICYQCSR PPPAHSKDLH STIVAAFQCT AAWLMQHPYL LQDKDCLQTV LEVVELGISG 120
  121 TKSQSKGTDI PKFKDEKELK PASMRVRDAA ENLLTIILEQ VGYFPSECGP ESISSLLDEL 180
  181 ALMKHCNSMV PAAAASSEQA IAKFKYFVTE NSTILALLEE PLGNDQDPQP TVTLLIRGPF 240
  241 GRHAWTMQLR HLPRSKSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1046-1426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKYHAINPGR PIPMNDVTQR LDSEQKNFPD GVDKVQPCVA DYSIPTIEQM REQYGTAVIR  60
   61 ELESLLENQS IHEKLAWAEA DTSADSLSHA QECVPPTVCH EFHAARLFLS HFGFLGFETR 120
  121 NPQNPAEALG NPPQRPLIVL DTKSAAFAAD LDRLDKLSAR THDSVYVFYV KSGQTSAQQI 180
  181 IANMGEESSA SHDPHFASML QTLGWPVQVS EHSGWTGFAH NSWSLKGTPE EQLKSTANEL 240
  241 NYNGSQRVLY WADVSSEIAF VVPTTWNLRY NSDTCDSGSI SSTDQIGSSN VWTRGEADSA 300
  301 AGLAKSKSRN LSLELDTNRR DVKEPVPPTR RKGNVTKPTL LAQAPAKIFL VWLESYEDYL 360
  361 NFPLEDLLAY TRTGEELQTQ Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.045757
Match: 1srqA
Description: Crystal Structure of the Rap1GAP catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #9
Region A:
Residues: [1427-1532]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPRASDCHVI FVHSLLSGLL RVKLQGPPGR MSFATPLVDG MVLSRRVVGN LVRQTALNIS  60
   61 RRRRLDNDNY QPPHVRRRLK VQDIVQKYKM DLSEADLLAH LFQRAI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.23
Match: 1srqA
Description: Crystal Structure of the Rap1GAP catalytic domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle