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Protein Overview: btd-PA

General Information:
Name(s) found: btd-PA / FBpp0071314 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene buttonhead is referred to in FlyBase by the symbol Dmel\btd (CG12653, FBgn0000233). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9588221..9591606. It has the cytological map location 8F10. There is experimental evidence that it has the molecular function</span>: transcription activator activity; transcription factor binding. There is experimental evidence that it is involved in the biological process</span>: positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; cephalic furrow formation; head segmentation. 25 alleles are reported. The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: peripheral nervous system; nervous system; antennal segment; adult segment; embryonic segment; organ system; organ system subdivision; external compound sense organ; embryonic head; abdominal lateral pentascolopidial chordotonal organ lch5. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 644 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    intracellular [IEA]
    Biological Process: specification of segmental identity, head [NAS]
    head segmentation [IMP]
    anterior head segmentation [TAS]
    posterior head segmentation [TAS]
    positive regulation of transcription, DNA-dependent [IDA]
    cephalic furrow formation [IMP]
    positive regulation of transcription from RNA polymerase II promoter [IDA]
    regulation of transcription from RNA polymerase II promoter [NAS]
    Molecular Function: nucleic acid binding [IEA]
    zinc ion binding [IEA]
    RNA polymerase II transcription factor activity [NAS]
    transcription activator activity [IDA]
    transcription factor binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIDAACNYLN PYAQQHQAQQ QQHAQHQQHA QQQQHHLHMQ QAQHHLHLSH QQAQQQHMQH  60
   61 LTQQQQQQQQ QQQQQQQQQQ QQQQPQQQQH DFLSAAALLS APPSLSGSSS GSSSGSSPLY 120
  121 GKPPMKLELP YPQASSTGTA SPNSSIQSAP SSASVSPSIF PSPAQSFASI SASPSTPTTT 180
  181 LAPPTTAAAG ALAGSPTSSS PSSSAASAAA AAAAAAAAAA DLGAAAVASA AYGWNTAYSG 240
  241 LGPARSQFPY AQYASDYYGN AVGMSSSAAW FSHQERLYQP WSSQSYPGFN FDDIAFQTQL 300
  301 QRRSVRCTCP NCTNEMSGLP PIVGPDERGR KQHICHIPGC ERLYGKASHL KTHLRWHTGE 360
  361 RPFLCLTCGK RFSRSDELQR HGRTHTNYRP YACPICSKKF SRSDHLSKHK KTHFKDKKSK 420
  421 KVLAAEAKEQ AAAAIKLEKK EKKSGKPLTP PVEFKQEQPD TTPLVNYAPY ANLYQHSTSA 480
  481 GSSVNPPPPP PPLFQQQMTT TTSSAAASFV EQPWSSSSSR AIQPATTSAS SSSSSSASSP 540
  541 AAAVVSAIGS ASSPAASATA LAQHHYAALA MQSESQLAAE YGLTMSGLAS GASQDSSSSC 600
  601 HMKSEYAASY PADFGAGTAS YGYPHPHPHH HNAWAAAYHP HATA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..89] FFAS03 2.41 A DESIGNED FOUR HELIX BUNDLE PROTEIN.
    2 View Details [90..239] deduced N/A No confident structure predictions are available.
    3 View Details [240..507] PSI-BLAST 53.30103 No description for 2i13A was found.
    4 View Details [508..644] MSA 1.440986 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.47

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle