Protein Overview: nej-PD, nej-PB

General Information:
Name(s) found:	nej-PD / FBpp0291863 [FlyBase] nej-PB / FBpp0071337 [FlyBase]
Description(s) found: Found 24 descriptions. SHOW ALL	The gene nejire is referred to in FlyBase by the symbol Dmel\nej (CG15319, FBgn0015624). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9563251..9581099. It has the cytological map location 8F7-8F9. There is experimental evidence that it has the molecular function</span>: histone acetyltransferase activity (H3-K27 specific); protein binding; transcription factor binding; histone acetyltransferase activity; histone acetyltransferase activity (H3-K18 specific); transcription coactivator activity. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: biopolymer modification; anatomical structure development; chromatin organization; protein modification process; sensory organ development; regulation of biological process; regulation of metabolic process; circadian rhythm; organ morphogenesis; cellular macromolecule metabolic process. 43 alleles are reported. The phenotypes of these alleles are annotated with 38 unique terms, many of which group under: peripheral nervous system; organ system; external compound sense organ; nervous system; adult segment; cephalopharyngeal skeleton; primordium; embryonic/larval tracheal system; cuticle; adult mesothoracic segment. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] The gene nejire is referred to in FlyBase by the symbol Dmel\nej (CG15319, FBgn0015624). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9563251..9581099. It has the cytological map location 8F7-8F9. There is experimental evidence that it has the molecular function</span>: histone acetyltransferase activity (H3-K27 specific); protein binding; transcription factor binding; histone acetyltransferase activity; histone acetyltransferase activity (H3-K18 specific); transcription coactivator activity. There is experimental evidence for 14 unique biological process</span> terms, many of which group under: biopolymer modification; anatomical structure development; chromatin organization; protein modification process; sensory organ development; regulation of biological process; regulation of metabolic process; circadian rhythm; organ morphogenesis; cellular macromolecule metabolic process. 43 alleles are reported. The phenotypes of these alleles are annotated with 38 unique terms, many of which group under: peripheral nervous system; organ system; external compound sense organ; nervous system; adult segment; cephalopharyngeal skeleton; primordium; embryonic/larval tracheal system; cuticle; adult mesothoracic segment. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	3276 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][ISS] protein complex [IPI] histone acetyltransferase complex [IEA]
Biological Process:	regulation of mitosis [IGI][IMP] hemopoiesis [TAS] smoothened signaling pathway [IMP][NAS] regulation of transcription, DNA-dependent [IEA] histone H4-K12 acetylation [IMP] histone H4-K8 acetylation [IMP] R7 cell differentiation [IMP] R3/R4 cell fate commitment [IMP] histone H3-K18 acetylation [IDA] positive regulation of transcription from RNA polymerase II promoter [IGI][IMP] regulation of transcription [IEA] histone H3-K27 acetylation [IDA] neurotransmitter secretion [IMP] synapse assembly [IMP] circadian regulation of gene expression [IMP] compound eye morphogenesis [IMP] locomotor rhythm [IMP] Wnt receptor signaling pathway [NAS]
Molecular Function:	cAMP response element binding protein binding [TAS] histone acetyltransferase activity [IDA] zinc ion binding [IEA] protein binding [IPI] transcription coactivator activity [IDA][IGI][ISS] transcription factor binding [IPI] histone acetyltransferase activity (H3-K18 specific) [IDA] histone acetyltransferase activity (H3-K27 specific) [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMADHLDEPP QKRVKMDPTD ISYFLEENLP DELVSSNSGW SDQLTGGAGG GNGGGGASGV  60
   61 TTNPTSGPNP GGGPNKPAAQ GPGSGTGGVG VGVNVGVGGV VGVGVVPSQM NGAGGGNGSG 120
  121 TGGDDGSGNG SGAGNRISQM QHQQLQHLLQ QQQQGQKGAM VVPGMQQLGS KSPNLQSPNQ 180
  181 GGMQQVVGTQ MGMVNSMPMS ISNNGNNGMN AIPGMNTIAQ GNLGNMVLTN SVGGGMGGMV 240
  241 NHLKQQPGGG GGGMINSVSV PGGPGAGAGG VGAGGGGAVA ANQGMHMQNG PMMGRMVGQQ 300
  301 HMLRGPHLMG ASGGAGGPGN GPGGGGPRMQ NPNMQMTQLN SLPYGVGQYG GPGGGNNPQQ 360
  361 QQQQQQQQLL AQQMAQRGGV VPGMPQGNRP VGTVVPMSTL GGDGSGPAGQ LVSGNPQQQQ 420
  421 MLAQQQTGAM GPRPPQPNQL LGHPGQQQQQ QQQPGTSQQQ QQQQGVGIGG AGVVANAGTV 480
  481 AGVPAVAGGG AGGAVQSSGP GGANRDVPDD RKRQIQQQLM LLLHAHKCNR RENLNPNREV 540
  541 CNVNYCKAMK SVLAHMGTCK QSKDCTMQHC ASSRQILLHY KTCQNSGCVI CYPFRQNHSV 600
  601 FQNANVPPGG GPAGIGGAPP GGGGAGGGAA GAGGNLQQQQ QQQQQQQQNQ QPNLTGLVVD 660
  661 GKQGQQVAPG GGQNTAIVLP QQQGAGGAPG APKTPADMVQ QLTQQQQQQQ QQVHQQQVQQ 720
  721 QELRRFDGMS QQVVAGGMQQ QQQQGLPPVI RIQGAQPAVR VLGPGGPGGP SGPNVLPNDV 780
  781 NSLHQQQQQM LQQQQQQGQN RRRGGLATMV EQQQQHQQQQ QQPNPAQLGG NIPAPLSVNV 840
  841 GGFGNTNFGG AAAGGAVGAN DKQQLKVAQV HPQSHGVGAG GASAGAGASG GQVAAGSSVL 900
  901 MPADTTGSGN AGNPNQNAGG VAGGAGGGNG GNTGPPGDNE KDWRESVTAD LRNHLVHKLV 960
  961 QAIFPTSDPT TMQDKRMHNL VSYAEKVEKD MYEMAKSRSE YYHLLAEKIY KIQKELEEKR1020
 1021 LKRKEQHQQM LMQQQGVANP VAGGAAGGAG SAAGVAGGVV LPQQQQQQQQ QQQQQGQQPL1080
 1081 QSCIHPSISP MGGVMPPQQL RPQGPPGILG QQTAAGLGVG VGVTNNMVTM RSHSPGGNML1140
 1141 ALQQQQRMQF PQQQQQQPPG SGAGKMLVGP PGPSPGGMVV NPALSPYQTT NVLTSPVPGQ1200
 1201 QQQQQFINAN GGTGANPQLS EIMKQRHIHQ QQQQQQQQQQ QGMLLPQSPF SNSTPLQQQQ1260
 1261 QQQQQQQQQQ QATSNSFSSP MQQQQQGQQQ QQQKPGSVLN NMPPTPTSLE ALNAGAGAPG1320
 1321 TGGSASNVTV SAPSPSPGFL SNGPSIGTPS NNNNNSSANN NPPSVSSLMQ QPLSNRPGTP1380
 1381 PYIPASPVPA TSASGLAASS TPASAAATCA SSGSGSNSSS GATAAGASST SSSSSAGSGT1440
 1441 PLSSVSTPTS ATMATSSGGG GGGGGNAGGG SSTTPASNPL LLMSGGTAGG GTGATTTTST1500
 1501 SSSSRMMSSS SSLSSQMAAL EAAARDNDDE TPSPSGENTN GSGGSGNAGG MASKGKLDSI1560
 1561 KQDDDIKKEF MDDSCGGNND SSQMDCSTGG GKGKNVNNDG TSMIKMEIKT EDGLDGEVKI1620
 1621 KTEAMDVDEA GGSTAGEHHG EGGGGSGVGG GKDNINGAHD GGATGGAVDI KPKTETKPLV1680
 1681 PEPLAPNAGD KKKKCQFNPE ELRTALLPTL EKLYRQEPES VPFRYPVDPQ ALGIPDYFEI1740
 1741 VKKPMDLGTI RTNIQNGKYS DPWEYVDDVW LMFDNAWLYN RKTSRVYRYC TKLSEVFEAE1800
 1801 IDPVMQALGY CCGRKYTFNP QVLCCYGKQL CTIPRDAKYY SYQNSLKEYG VASNRYTYCQ1860
 1861 KCFNDIQGDT VTLGDDPLQS QTQIKKDQFK EMKNDHLELE PFVNCQECGR KQHQICVLWL1920
 1921 DSIWPGGFVC DNCLKKKNSK RKENKFNAKR LPTTKLGVYI ETRVNNFLKK KEAGAGEVHI1980
 1981 RVVSSSDKCV EVKPGMRRRF VEQGEMMNEF PYRAKALFAF EEVDGIDVCF FGMHVQEYGS2040
 2041 ECPAPNTRRV YIAYLDSVHF FRPRQYRTAV YHEILLGYMD YVKQLGYTMA HIWACPPSEG2100
 2101 DDYIFHCHPT DQKIPKPKRL QEWYKKMLDK GMIERIIQDY KDILKQAMED KLGSAAELPY2160
 2161 FEGDFWPNVL EESIKELDQE EEEKRKQAEA AEAAAAANLF SIEENEVSGD GKKKGQKKAK2220
 2221 KSNKSKAAQR KNSKKSNEHQ SGNDLSTKIY ATMEKHKEVF FVIRLHSAQS AASLAPIQDP2280
 2281 DPLLTCDLMD GRDAFLTLAR DKHFEFSSLR RAQFSTLSML YELHNQGQDK FVYTCNHCKT2340
 2341 AVETRYHCTV CDDFDLCIVC KEKVGHQHKM EKLGFDIDDG SALADHKQAN PQEARKQSIQ2400
 2401 RCIQSLAHAC QCRDANCRLP SCQKMKLVVQ HTKNCKRKPN GGCPICKQLI ALCCYHAKNC2460
 2461 EEQKCPVPFC PNIKHKLKQQ QSQQKFQQQQ LLRRRVALMS RTAAPAALQG PAAVSGPTVV2520
 2521 SGGVPVVGMS GVAVSQQVIP GQAGILPPGA GGMSPSTVAV PSPVSGGAGA GGMGGMTSPH2580
 2581 PHQPGIGMKP GGGHSPSPNV LQVVKQVQEE AARQQVSHGG GFGKGVPMAP PVMNRPMGGA2640
 2641 GPNQNVVNQL GGMGVGVGGV GGVGVGGVGG VGVNQLNSGG GNTPGAPISG PGMNVNHLMS2700
 2701 MDQWGGGGAG GGGANPGGGN PQARYANNTG GMRQPTHVMQ TNLIPPQQQQ QMMGGLGGPN2760
 2761 QLGGGQMPVG GQHGGMGMGM GAPPMAGTVG GVRPSPGAGG GGGSATGGGL NTQQLALIMQ2820
 2821 KIKNNPTNES NQHILAILKQ NPQIMAAIIK QRQQSQNNAA AGGGAPGPGG ALQQQQAGNG2880
 2881 PQNPQQQQQQ QQQQQVMQQQ QMQHMMNQQQ GGGGPQQMNP NQQQQQQQVN LMQQQQQGGP2940
 2941 GGPGSGLPTR MPNMPNALGM LQSLPPNMSP GVSTQGGMVP NQNWNKMRYM QMSQYPPPYP3000
 3001 QRQRGPHMGG AGPGPGQQQF PGGGGGAGNF NAGGAGGAGG VVGVGGVPGG AGTVPGGDQY3060
 3061 SMANAAAASN MLQQQQGQVG VGVGVGVKPG PGQQQQQMGV GMPPGMQQQQ QQQQPLQQQQ3120
 3121 MMQVAMPNAN AQNPSAVVGG PNAQVMGPPT PHSLQQQLMQ SARSSPPIRS PQPTPSPRSA3180
 3181 PSPRAAPSAS PRAQPSPHHV MSSHSPAPQG PPHDGMHNHG MHHQSPLPGV PQDVGVGVGV3240
 3241 GVGVGVNVNV GNVGVGNAGG ALPDASDQLT KFVERL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.20

Protein Overview: nej-PD, nej-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: