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Protein Overview: l(1)G0232-PA

General Information:
Name(s) found: l(1)G0232-PA / FBpp0099554 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene lethal (1) G0232 is referred to in FlyBase by the symbol Dmel\l(1)G0232 (CG32697, FBgn0028341). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9522732..9552947. It has the cytological map location 8F2-8F6. Based on sequence similarity, it is predicted to have molecular function</span>: non-membrane spanning protein tyrosine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 25 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 827 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: phagocytosis, engulfment [IMP]
    protein amino acid dephosphorylation [IEA][NAS]
    Molecular Function: non-membrane spanning protein tyrosine phosphatase activity [ISS]
    protein tyrosine phosphatase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQTQWNKDR QEDRNNNSGS RSEQDSGCHR RLFLCIAKAV KQFIDLCNNL GANCSTTTAT  60
   61 SPSTSSSSAS STQNLIAVVP PQLQQLQVQL PAPGGGGGAG AGGGGGGGGG AAPVRRHISH 120
  121 TTAVKFLYAR KFDIPRAVSL YEQHEQIRLK EYLYNIDPDV EPLRSELQTG KFTILPARTS 180
  181 SGAAIALFTA NRHSPLSVSH TTTLQGIVYQ LDSALQDSET QRAGLVFIYD MSGSKYSNFD 240
  241 YDLSQKILTL LKGGYPARLK KVLIVTAPLW FKAPFKILRL FVREKLRERV FTVSVPQLAL 300
  301 HVPRKALPIH LGGTLEVDHA TWLLSCRQSM TNREDELLAN IVGVGGGSGS GSAAGSAAIV 360
  361 STNGTETEAA TTAATIISAV HQLGDNNTTV VTVSNGVGPA GSASGGATTA ASAATEPNEN 420
  421 ITINGLSPSH RQAANNSSSS SSSAATVANP LKLNTSGSAD NNSTITNATT AAGAAGAAAG 480
  481 TTTNGGGEFW SENPPSSASS GFSDDDSLAG QEGDPKPIDQ IVQMVKQRGR HGLIKEYADI 540
  541 RNRAPEGTFL HARMRANLTK NRYTDVLCYD HSRVVLAHED GDEPSDYINA NFVDGYKQKN 600
  601 AYISTQGPLP KTSQDFWRMI WEQHCLVIVM TTRVMERGRV KCGQYWEPTE ESSLEFGDYH 660
  661 VRTISVECNE DYMVASLELR NIKTDEIRNV SHWQFTSWPD YGVPSSAMAM LNFLQKVREK 720
  721 QAQLVQGLGD TWAGHPRGPP IVVHCSAGIG RTGTFITLDI CISRLEDVGT ADIRGTVEKI 780
  781 RSQRAYSIQM PDQYVFCHLA LIEYAYSRGM LQTVDLAGFD EREPDSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..72] deduced N/A No confident structure predictions are available.
    2 View Details [73..433] PSI-BLAST 42.522879 The Crystal Structure of Human Supernatant Protein Factor
    3 View Details [434..516] deduced N/A No confident structure predictions are available.
    4 View Details [517..827] PSI-BLAST 94.0 No description for 2pa5A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.50711590439337 bayes_pls_golite062009
  • transporter activity
    		•  2.25865143268098 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.10462277559464 bayes_pls_golite062009
  • vitamin binding
    		•  2.0152397506122 bayes_pls_golite062009
  • retinal binding
    		•  1.93254744702904 bayes_pls_golite062009
  • retinoid binding
    		•  1.8165604084023 bayes_pls_golite062009
  • isoprenoid binding
    		•  1.75796060899596 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.57333660473021 bayes_pls_golite062009
  • protein binding
    		•  1.43563365816744 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.14391953556505 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.663226199389531 bayes_pls_golite062009
  • protein transporter activity
    		•  0.338272481166365 bayes_pls_golite062009
  • lipid transporter activity
    		•  0.292848105509111 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle