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View Structure Prediction Details

Protein: l(1)G0232-PA
Organism: Drosophila melanogaster
Length: 827 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for l(1)G0232-PA.

Description E-value Query
Range
Subject
Range
l(1)G0232-PB - The gene lethal (1) G0232 is referred to in FlyBase by the symbol Dmel\l(1)G0232 (CG32697, FBgn00283...
558.0 [0..29] [827..4]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQQTQWNKDR QEDRNNNSGS RSEQDSGCHR RLFLCIAKAV KQFIDLCNNL GANCSTTTAT  60
   61 SPSTSSSSAS ST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [73-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNLIAVVPPQ LQQLQVQLPA PGGGGGAGAG GGGGGGGGAA PVRRHISHTT AVKFLYARKF  60
   61 DIPRAVSLYE QHEQIRLKEY LYNIDPDVEP LRSELQTGKF TILPARTSSG AAIALFTANR 120
  121 HSPLSVSHTT TLQGIVYQLD SALQDSETQR AGLVFIYDMS GSKYSNFDYD LSQKILTLLK 180
  181 GGYPARLKKV LIVTAPLWFK APFKILRLFV REKLRERVFT VSVPQLALHV PRKALPIHLG 240
  241 GTLEVDHATW LLSCRQSMTN REDELLANIV GVGGGSGSGS AAGSAAIVST NGTETEAATT 300
  301 AATIISAVHQ LGDNNTTVVT VSNGVGPAGS ASGGATTAAS AATEPNENIT INGLSPSHRQ 360
  361 A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.522879
Match: 1o6uA
Description: The Crystal Structure of Human Supernatant Protein Factor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.50711590439337 bayes_pls_golite062009
transporter activity 2.25865143268098 bayes_pls_golite062009
substrate-specific transporter activity 2.10462277559464 bayes_pls_golite062009
vitamin binding 2.0152397506122 bayes_pls_golite062009
retinal binding 1.93254744702904 bayes_pls_golite062009
retinoid binding 1.8165604084023 bayes_pls_golite062009
isoprenoid binding 1.75796060899596 bayes_pls_golite062009
transcription regulator activity 1.57333660473021 bayes_pls_golite062009
protein binding 1.43563365816744 bayes_pls_golite062009
transmembrane transporter activity 1.14391953556505 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.663226199389531 bayes_pls_golite062009
protein transporter activity 0.338272481166365 bayes_pls_golite062009
lipid transporter activity 0.292848105509111 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [434-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANNSSSSSSS AATVANPLKL NTSGSADNNS TITNATTAAG AAGAAAGTTT NGGGEFWSEN  60
   61 PPSSASSGFS DDDSLAGQEG DPK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [517-827]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIDQIVQMVK QRGRHGLIKE YADIRNRAPE GTFLHARMRA NLTKNRYTDV LCYDHSRVVL  60
   61 AHEDGDEPSD YINANFVDGY KQKNAYISTQ GPLPKTSQDF WRMIWEQHCL VIVMTTRVME 120
  121 RGRVKCGQYW EPTEESSLEF GDYHVRTISV ECNEDYMVAS LELRNIKTDE IRNVSHWQFT 180
  181 SWPDYGVPSS AMAMLNFLQK VREKQAQLVQ GLGDTWAGHP RGPPIVVHCS AGIGRTGTFI 240
  241 TLDICISRLE DVGTADIRGT VEKIRSQRAY SIQMPDQYVF CHLALIEYAY SRGMLQTVDL 300
  301 AGFDEREPDS E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 94.0
Match: 2pa5A
Description: No description for 2pa5A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle