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Protein Overview: l(1)G0232-PC

General Information:
Name(s) found: l(1)G0232-PC / FBpp0099556 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene lethal (1) G0232 is referred to in FlyBase by the symbol Dmel\l(1)G0232 (CG32697, FBgn0028341). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9522732..9552947. It has the cytological map location 8F2-8F6. Based on sequence similarity, it is predicted to have molecular function</span>: non-membrane spanning protein tyrosine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 25 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 797 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: phagocytosis, engulfment [IMP]
    protein amino acid dephosphorylation [IEA][NAS]
    Molecular Function: non-membrane spanning protein tyrosine phosphatase activity [ISS]
    protein tyrosine phosphatase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAEQQEFAV KQFIDLCNNL GANCSTTTAT SPSTSSSSAS STQNLIAVVP PQLQQLQVQL  60
   61 PAPGGGGGAG AGGGGGGGGG AAPVRRHISH TTAVKFLYAR KFDIPRAVSL YEQHEQIRLK 120
  121 EYLYNIDPDV EPLRSELQTG KFTILPARTS SGAAIALFTA NRHSPLSVSH TTTLQGIVYQ 180
  181 LDSALQDSET QRAGLVFIYD MSGSKYSNFD YDLSQKILTL LKGGYPARLK KVLIVTAPLW 240
  241 FKAPFKILRL FVREKLRERV FTVSVPQLAL HVPRKALPIH LGGTLEVDHA TWLLSCRQSM 300
  301 TNREDELLAN IVGVGGGSGS GSAAGSAAIV STNGTETEAA TTAATIISAV HQLGDNNTTV 360
  361 VTVSNGVGPA GSASGGATTA ASAATEPNEN ITINGLSPSH RQAANNSSSS SSSAATVANP 420
  421 LKLNTSGSAD NNSTITNATT AAGAAGAAAG TTTNGGGEFW SENPPSSASS GFSDDDSLAG 480
  481 QEGDPKPIDQ IVQMVKQRGR HGLIKEYADI RNRAPEGTFL HARMRANLTK NRYTDVLCYD 540
  541 HSRVVLAHED GDEPSDYINA NFVDGYKQKN AYISTQGPLP KTSQDFWRMI WEQHCLVIVM 600
  601 TTRVMERGRV KCGQYWEPTE ESSLEFGDYH VRTISVECNE DYMVASLELR NIKTDEIRNV 660
  661 SHWQFTSWPD YGVPSSAMAM LNFLQKVREK QAQLVQGLGD TWAGHPRGPP IVVHCSAGIG 720
  721 RTGTFITLDI CISRLEDVGT ADIRGTVEKI RSQRAYSIQM PDQYVFCHLA LIEYAYSRGM 780
  781 LQTVDLAGFD EREPDSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..443] PSI-BLAST 44.30103 The Crystal Structure of Human Supernatant Protein Factor
    2 View Details [444..797] PSI-BLAST 92.221849 No description for 2pa5A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.50711590439337 bayes_pls_golite062009
  • transporter activity
    		•  2.25865143268098 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.10462277559464 bayes_pls_golite062009
  • vitamin binding
    		•  2.0152397506122 bayes_pls_golite062009
  • retinal binding
    		•  1.93254744702904 bayes_pls_golite062009
  • retinoid binding
    		•  1.8165604084023 bayes_pls_golite062009
  • isoprenoid binding
    		•  1.75796060899596 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.57333660473021 bayes_pls_golite062009
  • protein binding
    		•  1.43563365816744 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.14391953556505 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.663226199389531 bayes_pls_golite062009
  • protein transporter activity
    		•  0.338272481166365 bayes_pls_golite062009
  • lipid transporter activity
    		•  0.292848105509111 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle