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Protein Overview: ric8a-PA, FBpp03...

General Information:
Name(s) found: FBpp0311994 [FlyBase]
ric8a-PA / FBpp0071252 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=X:join(9150330..9150410,9150476..9152116); ID=FBpp0311994; name=ric8a-PB; parent=FBgn0028292,FBtr0346166; dbxref=FlyBase:FBpp0311994,FlyBase_Annotation_IDs:CG15797-PB; MD5=8814accd38c537085738a4d9e0ddca4c; length=573; release=r5.56; species=Dmel; [FlyBase]
  • The gene ric8a is referred to in FlyBase by the symbol Dmel\ric8a (CG15797, FBgn0028292). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9150224..9152708. It has the cytological map location 8D3. There is experimental evidence that it has the molecular function</span>: G-protein alpha-subunit binding. There is experimental evidence that it is involved in the biological process</span>: establishment or maintenance of cell polarity; protein stabilization; gastrulation involving germ band extension; establishment of mitotic spindle localization; asymmetric neuroblast division; asymmetric protein localization; asymmetric cell division. 11 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 573 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA]
    cytosol [IDA]
    Biological Process: establishment of mitotic spindle localization [IMP]
    establishment or maintenance of cell polarity [IMP]
    asymmetric cell division [IMP]
    asymmetric neuroblast division [IMP]
    protein stabilization [IMP]
    gastrulation involving germ band extension [IMP]
    asymmetric protein localization [IMP]
    Molecular Function: G-protein alpha-subunit binding [IPI]
    guanyl-nucleotide exchange factor activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METEHLKRLE AKEADHIPAI LDEFNTKNAD LLVFDSFRTD NLWHELWLAI FGILDDQRLS  60
   61 HLHTQCLNTV RILTRDEFSL QTNYIEQEVN TLLKLARIEA GSLKLPATPD ELKQEEREEP 120
  121 QLEPSQAQSE VIAEALKCLC NLVYQSSDCR RQCLRQHCLD AILKRVASSM RHPCALEYYD 180
  181 MKLLFLLTAL EPAARSRLQI DLNGLTYMTK WLDDKLGEDS VGEEQLNIIC ELLKVMFNVT 240
  241 SAPDKSPNEY EIQSLHLTGV LRELLLRFGD LATEKDRAVV THAINLLTNI SGSCLTELTL 300
  301 RCSNAELESH KEREQDNEKE KDTEAGAGAK PRECCSQCFE KRNVRSLDVL LRYLRQSLAQ 360
  361 QEAEASSHEL LSPVLTVLVK CARSDRVMRH YLRQEILPPL RDVSQRPEVG QELRNHLCRF 420
  421 LTLPAMILRD LSAELLFVLC KENVGRMIKY TGYGNAAGLF AKRGILDCRR VEGTDYSSDS 480
  481 EDSDTEEYKQ QQQGINPVLG CVEPRSKSHL DDISEEQKEY EAMQLVNLIE QLRQGGIVKP 540
  541 AMIDKDGRPQ PLEHILQLQE ELPQQQLDQK RKT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..573] FFAS03 1.13 No description for 2gl7A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  2.39228656281234 bayes_pls_golite062009
  • transporter activity
    		•  2.33552524809949 bayes_pls_golite062009
  • binding
    		•  2.32095856197757 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.84332793919001 bayes_pls_golite062009
  • protein binding
    		•  1.61131270705552 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.42084326734073 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.23535249814494 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.07458868889742 bayes_pls_golite062009
  • signal transducer activity
    		•  1.07458868889742 bayes_pls_golite062009
  • peptide binding
    		•  0.945352966332572 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.77593418182529 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.688926699413612 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.646859295714843 bayes_pls_golite062009
  • DNA binding
    		•  0.604001085938821 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.229435071193924 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.187924119511902 bayes_pls_golite062009
  • receptor binding
    		•  0.109094659157491 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle