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Protein Overview: Ost48-PA

General Information:
Name(s) found: Ost48-PA / FBpp0071279 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Oligosaccharyltransferase 48kD subunit is referred to in FlyBase by the symbol Dmel\Ost48 (CG9022, FBgn0014868). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9050955..9052544. It has the cytological map location 8C14. Based on sequence similarity, it is predicted to have molecular function</span>: dolichyl-diphosphooligosaccharide-protein glycotransferase activity. It is reported to be involved in the biological process</span>: protein amino acid N-linked glycosylation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 449 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [IEA]
    lipid particle [IDA]
    Biological Process: protein amino acid N-linked glycosylation [NAS]
    protein amino acid N-linked glycosylation via asparagine [IEA]
    Molecular Function: dolichyl-diphosphooligosaccharide-protein glycotransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMWKALLIAV LAIAHCQAVL ETDANTLVLL DNLAIRETHS IFFKSLQDRG FKLTYKLADD  60
   61 SSLLLSKYGE YLYKNVIIFA PSVEEFGGDV SVERLAQFVD DGGNVLVAGS EKSGDALREF 120
  121 ASECGFELDE ENAAVIDHLH YDVSDAGEHT TILTSAKNLI QADTIVGKAN RQADAAPLLY 180
  181 RGTGLIADKE NPLVLKLLTA ESTAYSYNPE ASVSDYPHAV GRGTLLIAAL QARNNARVVF 240
  241 SGSLLFFSDE SFTTAVQYAQ SGVFHKLAGN RDVAESISKW VFGETGRLRV ASVQHHKEGE 300
  301 LLPPDQAYTI TDPVVYTIGI EELVQGEWRA FKASDIQLEF VRIDPFVRTY LKQTNTGAYQ 360
  361 AKFKIPDVYG VYQFKVDYNR VGYTHLYSTT QVSVRPLEHT QYERFIPSAF PYYTSAFSMM 420
  421 IGVFVFSFVF LHFKDEPVGR AAKEDKKSQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..304] FFAS03 1.04 No description for 2gk3A was found.
    2 View Details [305..449] MSA 2.042961 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.21522719658673 bayes_pls_golite062009
  • binding
    		•  1.10799322720495 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.00678459791194 bayes_pls_golite062009
  • ligase activity
    		•  0.952686615697528 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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