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Protein Overview: spirit-PC, spiri...

General Information:
Name(s) found: FBpp0304874 [FlyBase]
spirit-PC / FBpp0289955 [FlyBase]
spirit-PA / FBpp0071175 [FlyBase]
spirit-PB / FBpp0071174 [FlyBase]
Description(s) found:
Found 50 descriptions.
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  • type=protein; loc=X:complement(8465371..8466001,8466124..8466340,8466492..8466746,8466861..8466939); ID=FBpp0304874; name=spirit-PD; parent=FBgn0030051,FBtr0332628; dbxref=REFSEQ:NP_001259342,GB_protein:AGB95185,FlyBase:FBpp0304874,FlyBase_Annotation_IDs:CG2056-PD; MD5=45511ba498cf5e795f69db5fe74c9daf; length=393; release=r5.56; species=Dmel; [FlyBase]
  • The gene Serine Protease Immune Response Integrator is referred to in FlyBase by the symbol Dmel\spirit (CG2056, FBgn0030051). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8465132..8467614. It has the cytological map location 7F5. It is reported to have molecular function</span>: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: defense response to fungus; innate immune response; defense response to Gram-positive bacterium; defense response to Gram-negative bacterium; positive regulation of Toll signaling pathway. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Serine Protease Immune Response Integrator is referred to in FlyBase by the symbol Dmel\spirit (CG2056, FBgn0030051). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8465132..8467614. It has the cytological map location 7F5. It is reported to have molecular function</span>: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: defense response to fungus; innate immune response; defense response to Gram-positive bacterium; defense response to Gram-negative bacterium; positive regulation of Toll signaling pathway. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Serine Protease Immune Response Integrator is referred to in FlyBase by the symbol Dmel\spirit (CG2056, FBgn0030051). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8465132..8467614. It has the cytological map location 7F5. It is reported to have molecular function</span>: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: defense response to fungus; innate immune response; defense response to Gram-positive bacterium; defense response to Gram-negative bacterium; positive regulation of Toll signaling pathway. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 393 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: defense response to Gram-negative bacterium [IMP]
    innate immune response [IMP]
    proteolysis [IEA][NAS]
    positive regulation of Toll signaling pathway [IMP]
    defense response to fungus [IMP]
    defense response to Gram-positive bacterium [IMP]
    Molecular Function: serine-type endopeptidase activity [IEA][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIRSTHCIP TRVYLHLLLV SLPLLAVHAT PAISPQSLRG IIFPVETFDE CQLEDVARTK  60
   61 GTCRRMEDCP SALNGWLERR ESPKTCYFVR FDHYVCCAPA VAPIVTRSSQ QACNELNKVS 120
  121 KVKEIDEFFV SVVGGMPTRP REFPFMAALG WRSNFDQRIY YRCGGALIAN NFVLTAAHCA 180
  181 DLGGEPPSQV RLGGDNLTLT EGEDISIRRV IIHPDYSAST AYNDIALLEL ETAAKPELKP 240
  241 TCIWTQKEVT NTLVTAIGYG QTSFAGLSSA QLLKVPLKSV SNEECQHHYQ KDQLAQGVLG 300
  301 TQMCAGDITG ERDTCQGDSG GPLLMQDGLL GYVVGITSLG QGCASGPPSV YTRVSSFVDW 360
  361 IEGIVWPAQQ VTNAPQPNQM TSFSPEFDLR ATI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..393] PSI-BLAST 56.69897 No description for 2f83A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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